RE: Standard errors below 0.1%?

From: "Bachman, William (MYD)" bachmanw@iconus.com Subject: RE: [NMusers] Standard errors below 0.1%? Date: Wed, 3 Aug 2005 08:05:29 -0400 Changing the TOL effectively changes the search over the response surface (lowering the tolerance allows termination with less stringent criteria) which, as in your case, can result in a successful covariance step. As far as the standard error estimates, one should use all the information at hand to assess the the model including the variance estimates and diagnostic plots. Are the low std error estimates corroborated by tight plots or, conversely, are they all over the place. (That information is really more related to the variance estimates, but, if you have highly informative data you will get low std error estimates). I haven't looked at your model thoroughly and without assessing all the estimates and seeing diagnostic plots, it's difficult to know if your std estimates should be trusted. However, it's UNUSUAL for Michaelis-Menten type parameters to be well estimated.