RE: Renal CL estimations

From: Leonid Gibiansky lgibiansky@emmes.com Subject: RE:[NMusers] Renal CL estimations Date: Wed, June 16, 2004 8:34 am A(2) is the drug collected in the urine compartment. So you can include total amount found in urine within 24 hours into the data set at time 24 as A(2) (you need to use appropriate values of the CMT data item to code it, CMT=1 for the central compartment observation and CMT=2 for the A2 observations). Similarly, if you have cumulative A2 data from time 0 to time t, you can include those at time t (at the end of the urine collection interval). If you have sample urine data (not cumulative) you need to reset the A2 compartment to 0 at each A2 measurement (assuming that this time coincides with the start of the new urine sample collection interval) Leonid _______________________________________________________