Fitting Data Below the Quantification Limit

From: Matt Hutmacher Date: January 06, 2004 technical Source: cognigencorp.com
From: "Hutmacher, Matt" - mhutmach@amgen.com Subject: [NMusers] Fitting Data Below the Quantification Limit Date: 1/6/2004 6:23 PM Hello all, I was wondering if anyone has experience fitting PK Models where some data are below the quantification limit. Specifically, if anyone has attempted to fit the censored likelihoods that are described in Stuart Beal's JPP manuscript, JPP 2001; 28 481-504. If you have any NONMEM code or implementation suggestions it would be greatly appreciated. Thanks, Matt

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Jan 06, 2004 Matt Hutmacher Fitting Data Below the Quantification Limit
Jan 10, 2004 Lewis B. Sheiner RE: Fitting Data Below the Quantification Limit
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