Re: Different population estimates

From: Toufigh Gordi tgordi@buffalo.edu Subject: Re: [NMusers] Different population estimates Date: 11/17/2003 2:32 PM The duration is the same for all. When I run the PK model alone, i.e. estimated PK parameters in a separate model, population predictions are exactly the same for individuals in each dose cohort. I also notice from a couple of subjects that their (predicted) PK profile is slightly changed depending on if it is generated by the final model (simultaneous PK/PD) or PK model alone. I find it quite natural since there should be some PK information in PD data and that is why I estimate all parameters simultaneously. I will add INTERACTION in the model. Thanks for the suggestion. Toufigh