RE: Model estimates based on 1 sample per subject

From: lgibiansky@emmes.com Subject: RE: [NMusers] Model estimates based on 1 sample per subject Date: 8/19/2003 5:03 PM Toufigh, I think you will need to provide more info concerning your model (e.g., NONMEM control stream and data sample). Otherwise, it is difficult to discuss the problem without knowing what exactly you are trying to do. In general, NONMEM can fit nonlinear model without difficulties. If you have one sample per animal, you cannot fit population model, you will need to approach this as an "average" pooled data fit. In this case you should not face problems if your data support the model (i.e., describe the full profile). Leonid