RE: Mixture models in NONMEM

From: Atul Bhattaram Venkatesh Date: April 17, 2003 technical Source: cognigencorp.com
From: "Bhattaram, Atul" Subject:RE: [NMusers] Mixture models in NONMEM Date:Thu, 17 Apr 2003 16:32:13 -0400 Hello Rajesh It would be interesting to know why you selected MIXTURE model. Was it based on some prior information (phenotype) or some assumption testing. I remember a reference in which they used MIXTURE model because they had polymorphism in metabolism. Use of mixture model might help in identifying why you have two proportions which must be reflected as bimodality etc in your plots. Venkatesh Atul Bhattaram CDER, FDA.

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Apr 17, 2003 Unknown Mixture models in NONMEM
Apr 17, 2003 Atul Bhattaram Venkatesh RE: Mixture models in NONMEM
Apr 17, 2003 Sam Liao RE: Mixture models in NONMEM
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