Re: Oral pharmacokinetics sparse (no absorption phase)
From: Leonid Gibiansky
Subject: Re: [NMusers] Oral pharmacokinetics sparse (no absorption phase)
Date: Wed, 08 May 2002 09:30:34 -0400
Atul,
If you compare two solutions given to you by NONMEM (S+ script for population curves
is given below) you will see that they cannot be distinguished even given the dense PK
data (they are nearly identical except 10% difference in Cmax). You need IV data or
previous knowledge to sort this out.
Leonid.