Re: Oral pharmacokinetics sparse (no absorption phase)

From: Leonid Gibiansky Date: May 08, 2002 technical Source: cognigencorp.com
From: Leonid Gibiansky Subject: Re: [NMusers] Oral pharmacokinetics sparse (no absorption phase) Date: Wed, 08 May 2002 09:30:34 -0400 Atul, If you compare two solutions given to you by NONMEM (S+ script for population curves is given below) you will see that they cannot be distinguished even given the dense PK data (they are nearly identical except 10% difference in Cmax). You need IV data or previous knowledge to sort this out. Leonid.
May 08, 2002 Atul Bhattaram Venkatesh Oral pharmacokinetics sparse (no absorption phase)
May 08, 2002 Leonid Gibiansky Re: Oral pharmacokinetics sparse (no absorption phase)
May 08, 2002 William Bachman RE: Oral pharmacokinetics sparse (no absorption phase)