Re: Non-zero peripheral drug amount

From: Kazimierz Date: October 03, 2001 technical Source: cognigencorp.com

From: Kazimierz <khkoz@czd.waw.pl> Subject: Re: Non-zero peripheral drug amount Date: Wed, 03 Oct 2001 16:45:44 +0200 Dear Professor Holford, I have used this formula for modelling Vd of Ganciclovir in newborns and infants (Kozlowski KH et al. PAGE2001) and have >10 years experiences. BSA(m2)=(HT(cm)*WGT(kg))**0.5/60 it uses geometric mean of HT and WGT Alternative option for inches also exists. References: Mosteller RD.N.Engl.J.Med. 317(17), 1098, 1987 - original Lam TK et. al.: -//- 318(17), 1130, 1988 Clin Pharmacol. Ther. 69, 145-57, 2001 - application for PK Sincerely Kazimierz H. Kozlowski, Warsaw, Poland

Oct 02, 2001	Paul Hutson	Non-zero peripheral drug amount
Oct 02, 2001	Nick Holford	Re: Non-zero peripheral drug amount
Oct 03, 2001	Kazimierz	Re: Non-zero peripheral drug amount
Oct 03, 2001	Paul Hutson	Re: Non-zero peripheral drug amount - solution

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Re: Non-zero peripheral drug amount

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