NONMEM Timeline
From: stuart@c255.ucsf.edu
Subject: NONMEM Timeline
Date: Tue, 14 Aug 2001 06:31:17 -0700 (PDT)
NONMEM Timeline
1977 PROTO, the prototype computer program preceding NONMEM
1978 First data analysis results published using PROTO
(P. Ravenscroft et al, "Saliva lithium concentrations in the management
of lithium therapy", Archives of General Psychiatry, 35)
1979 NONMEM, exportable for IBM mainframe computer
first documented distribution to: Dr. Donald Stanski
1980 NONMEM announced in publication (SL Beal and LB Sheiner, "The
NONMEM System", The American Statistician, 34)
1981 First NONMEM Course in US
1982 First data analysis results using NONMEM
(S. Vozeh et al, "Population pharmacokinetic parametersa in patients
treated with oral mexiletine", Eur. J. Clin. Pharmacol, 23)
1984 NONMEM Version I, exportable for all computers
Software licensed by the University of California
1st distribution to: Dr. Tom Ludden
1985 NONMEM Version II, with first version of PREDPP
1985 First NONMEM Course outside US (Univ. of Uppsala)
1989 NONMEM Version III, with first version of NM-TRAN
1992 NONMEM Users Net established
Archiving of discussions undertaken by Dr. David Bourne
1992 NONMEM Version IV, with first appearance of conditional estimation
methods
1994 NONMEM Repository established by Drs. Steve Shafer and Jaap Mandema
1997 NONMEM Archive formally maintained by Pharmaceutical Outcomes
Research (today known as Cognigen)
1998 NONMEM Version V, with first appearance of setup tools and Help Guide
1998 The acronym 'NONMEM' is US trademarked
2001 1000th distribution to:
Wan Gyoon Shin
Seoul National University, Korea
Other Data:
Earliest NONMEM Enthusiast (other than the developers):
Dr. Sidney Reigelman
University of California at San Francisco, US
Individual with most published NONMEM data analyses:
Dr. Mats Karlsson
University of Uppsala, Sweden
Number of published NONMEM data analyses at last tally: 322