Rounding errors

From: Paul Hutson <prhutson@pharmacy.wisc.edu> Subject: Rounding errors Date: Fri, 23 Mar 2001 10:28:35 -0600 Ken: By modifying the variance/covariance structure, do you suggest removing etas, or changing the structure, such as going from TVCL=THETA(1)*EXP(ETA(1)) to TVCL=THETA(1)+ETA(1) (recognizing the risk of a negative value for TVCL)? Thanks Paul Hutson Paul Hutson, Pharm.D. Associate Professor (CHS) UW School of Pharmacy 425 N. Charter St Madison, WI 53706-1515 Tel: (608) 263-2496 FAX: (608) 265-5421 Pager: (608) 265-7000, #7856