RE: 95% CI of paramter estimate
From: "Piotrovskij, Vladimir [JanBe]" <VPIOTROV@janbe.jnj.com>
Subject: RE: 95% CI of paramter estimate
Date: Tue, 21 Nov 2000 09:05:54 +0100
Dear NM-users,
A couple of relevant references on bootstrapping in mixed-effects PK modeling:
1. Yafune A. Ishiguro M. Bootstrap approach for constructing confidence intervals for population pharmacokinetic parameters. I: A use of bootstrap standard error. Statistics in Medicine. 18(5):581-599. 1999.
2. ---. Bootstrap approach for constructing confidence intervals for population pharmacokinetic parameters. II: A bootstrap modification of standard two-stage (STS) method for phase I trial. Statistics in Medicine. 18(5):601-612. 1999.
Best regards,
Vladimir