Re: Caution with verbatim code/RE: Number of evaluations of differential equations

From: phil.lowe@pharma.Novartis.com Subject: Re: Caution with verbatim code/RE: Number of evaluations of differential equations Date: Thu, 31 Aug 2000 16:21:08 +0000 Dear Marc, many thanks for pointing out the issue with the single missed space. NONMEM now responds to changes in the specified number IMAX, such that I can now run my simulations without adding extra dummy samples "to fill in the gaps". I did not need to add too many more evaluations to get the system to run OK, just enough to get the PD function to turn a rather sharp corner just after the start of the drug administration (the response starts very quickly, reducing from a baseline value, leveling out close to zero, then recovering). Best regards, Phil.