Intrepretation of Dosing Intervals

I need to clarify how the program interprets dosing intervals. Suppose I have a dose given at 8:00 and indicate steady state with a dosing interval of 8 hrs, but my level is obtained at 16:15, 8 1/4 hours later, does the program assume that a dose was given at 16:00 and my 16:15 level is actually a 15 minute level? In most dosing scheems even if it is stated the drug is given Q8 the doses are ofter 8:00 16:00 and 22:00 (especially in the pediactric population). If I have the dosing information, I have been coding it like this. Date Time Dose SS II DV 9/1/94 08:00 200 1 24 0 9/1/94 16:00 200 1 24 0 9/1/94 22:00 200 1 24 0 9/2/94 07:59 0 0 0 23 I don't know how the program would respond if I entered it like this. 9/1/94 22:00 200 1 8 0 9/2/94 07:59 0 0 0 23 because the interval between dose and level is actually 10 hours. I have population data with the majority of levels drawn at trough concentrations. I am wondering if my approach is correct.