WFN for NONMEM 7.2.0 - version 720

Hi, I have uploaded a new version of Wings for NONMEM (version 720) to http://wfn.sourceforge.net/ . Please let me know when you find bugs. Nick This version is for use only with NONMEM 7.2. It does not work with NONMEM 7.1. NONMEM 7.2 has a number of optional arguments to the/nmfe72.bat/command e.g. nmfe72infileoutfile[-background] [-PARAFILE=file.pnm] [-licfile=filename] [-prsame] [-prdefault] [-prcompile] [-trskip] [-rundir=dirname][-runpdir=dirname] [-nmexec=filename] [-xmloff] The wfn7 commands for executing NONMEM remain simple with just one argument (the/runname/) e.g. nmgorunname Optional arguments for NONMEM 7.2 should be specified in an environment variable called ARGS7 e.g. setARGS7=-prdefault The –prdefaultvalue will restore the usual behavior of previous versions of NONMEM and skip the dynamic resizing process (which may add a substantial overhead to total runtimes). It is suggested that this command be added at the start of the/wfn.bat/file (see/wfn.txt/). The ARGS7 variable can be changed at any time before running wfn7 commands that execute NONMEM (e.g./nmgo//,nmbs,nmgosim/). Both file (fpi) and message passing interfaces (mpi) have been tested with wfn7. Theparafiles(wfn_fpi2.pnm, wfn_mpi2.pnm, wfn_fpi8.pnm, wfn_mpi8.pnm) in the/%wfnhome%\run/folder may be used as templates. Set the ARGS7 variable to theparafilename before running NONMEM e.g. if you have a two core computer with MPICH2 installed enter these commands: set ARGS7=”-parafile=wfn_mp2.pnm” nmgotheopd Note that the quotation marks around theparafileargument are required. Theparafilemust be put in the same folder as the run control stream file used by WFN. Do not use the –nmexecoption because WFN uses that to create a NONMEM executable using the/runname/. SeeInstallation http://wfn.sourceforge.net/wfninst.htmfor examples of testingfpiandmpimethods. Other Changes Formatting of/nmobj/command no longer attempts to show results when run folder does not contain a .smyfile. /nmbs/command now allows/runnames/with %NMCTL% extension e.g.nmbstheopd.ctl 1 1000ornmbstheopd1 1000are equivalent Bug in/nminstall.bat/for installing updates has been fixed. The installation destination directory is created if it does not already exist. -- Nick Holford, Professor Clinical Pharmacology Dept Pharmacology& Clinical Pharmacology University of Auckland,85 Park Rd,Private Bag 92019,Auckland,New Zealand tel:+64(9)923-6730 fax:+64(9)373-7090 mobile:+64(21)46 23 53 email: [email protected] http://www.fmhs.auckland.ac.nz/sms/pharmacology/holford

Hi, [This may be the second time you have seen this. However, it seems that some of my mails to nmusers are not being sent out to the list. If you see this and you use WFN please let me know] I have uploaded a new version of Wings for NONMEM (version 720) to http://wfn.sourceforge.net/ . Please let me know when you find bugs. Nick This version is for use only with NONMEM 7.2. It does not work with NONMEM 7.1. NONMEM 7.2 has a number of optional arguments to the/nmfe72.bat/command e.g. nmfe72infileoutfile[-background] [-PARAFILE=file.pnm] [-licfile=filename] [-prsame] [-prdefault] [-prcompile] [-trskip] [-rundir=dirname][-runpdir=dirname] [-nmexec=filename] [-xmloff] The wfn7 commands for executing NONMEM remain simple with just one argument (the/runname/) e.g. nmgorunname Optional arguments for NONMEM 7.2 should be specified in an environment variable called ARGS7 e.g. setARGS7=-prdefault The –prdefaultvalue will restore the usual behavior of previous versions of NONMEM and skip the dynamic resizing process (which may add a substantial overhead to total runtimes). It is suggested that this command be added at the start of the/wfn.bat/file (see/wfn.txt/). The ARGS7 variable can be changed at any time before running wfn7 commands that execute NONMEM (e.g./nmgo//,nmbs,nmgosim/). Both file (fpi) and message passing interfaces (mpi) have been tested with wfn7. Theparafiles(wfn_fpi2.pnm, wfn_mpi2.pnm, wfn_fpi8.pnm, wfn_mpi8.pnm) in the/%wfnhome%\run/folder may be used as templates. Set the ARGS7 variable to theparafilename before running NONMEM e.g. if you have a two core computer with MPICH2 installed enter these commands: set ARGS7=”-parafile=wfn_mp2.pnm” nmgotheopd Note that the quotation marks around theparafileargument are required. Theparafilemust be put in the same folder as the run control stream file used by WFN. Do not use the –nmexecoption because WFN uses that to create a NONMEM executable using the/runname/. SeeInstallation http://wfn.sourceforge.net/wfninst.htmfor examples of testingfpiandmpimethods. Other Changes Formatting of/nmobj/command no longer attempts to show results when run folder does not contain a .smyfile. /nmbs/command now allows/runnames/with %NMCTL% extension e.g.nmbstheopd.ctl 1 1000ornmbstheopd1 1000are equivalent Bug in/nminstall.bat/for installing updates has been fixed. The installation destination directory is created if it does not already exist. -- Nick Holford, Professor Clinical Pharmacology Dept Pharmacology& Clinical Pharmacology University of Auckland,85 Park Rd,Private Bag 92019,Auckland,New Zealand tel:+64(9)923-6730 fax:+64(9)373-7090 mobile:+64(21)46 23 53 email:[email protected] http://www.fmhs.auckland.ac.nz/sms/pharmacology/holford