Dear all,
just 2 questions:
1. Could anyone explain what DVIV and DVN mean in visual predective check(VPC)?
2. I try to run VPC with only items: ID TIME DV CMT EVID MDV, and i specified my output file to ".fit" form and in the same path where Perc_V01.pl is (perl version 10). The result was ERROR: NO FIT-files found. I set $my_fit_files_are_in_which_folder=0".
thanks in advance.
khaled
Visual predictive check
Dear Khaled,
Thank you very much for your question on my perl script for VPCs.
DVID (DVIV) is an identifier to the type of dependent variable.
This is NOT a NONMEM defined item. So the following
definition is arbitrary:
DVID = 0: Dose event
DVID = 1: e.g. Plasma concentration
DVID = 2: e.g. urine concentration
DVID = 3: any other type of observation
DVN is dose normalized concentration in the first example
of this perl script release. It is helpful to dose normalize
concentrations, if your subjects received different doses and
if your drug follows linear PK.
For question 2:
Your Perl installation should be fine, as you get the log-file.
I tried it right now on my computer and option 1 worked for me.
There are two options in the current version of the script:
Option 1:
$my_fit_files_are_in_which_folder = 0;
This setting assumed that the perl script Perc_V01.pl and
the *.fit file are in the same folder.
Please make sure you have the semicolon at the end of the
line. Otherwise the script will not run.
Option 2:
$my_fit_files_are_in_which_folder = 1;
This setting assumes that the perl script Perc_V01.pl is in
the main folder and that the fit files are in one or many sub-folders to
the main folder. This is helpful, if you use Nick's Wings For NONMEM.
Please check line 223 of the script:
@subfoldername = ( ".std", ".s7t", ".50t", ".57t", "g77" );
and have a look at the ending of the subfolders which are created
by your Wings For NONMEM installation. If the folder ends e.g. with
".df", then you will have to add this like that:
@subfoldername = ( ".std", ".s7t", ".50t", ".57t", "g77", "df" );
If you run this perl script, it is more convenient to see what is going
on, if you launch it from a DOS window, as you can see any error messages
more quickly. These also get printed to the log-file.
Hope it runs on your computer. Please give me a call if not.
Best wishes
Juergen
-----Ursprüngliche Nachricht-----
Von: "Khaled Mohammed Abduljalil" <[EMAIL PROTECTED]>
Gesendet: 07.05.08 11:46:54
An: [email protected]
Betreff: [NMusers] Visual predictive check
Dear all,
just 2 questions:
1. Could anyone explain what DVIV and DVN mean in visual
predective check(VPC)?
2. I try to run VPC with only items: ID TIME DV CMT EVID
MDV, and i specified my output file to ".fit" form and in
the same path where Perc_V01.pl is (perl version 10). The
result was
ERROR: NO FIT-files found. I set
$my_fit_files_are_in_which_folder=0".
thanks in advance.
khaled