Simulation step

2 messages 2 people Latest: Oct 22, 2001

Simulation step

From: Josep Maria Cendros Date: October 22, 2001 technical
From: josep-maria.cendros@beaufour-ipsen.com Subject: [NMusers] Simulation step Date: Mon, 22 Oct 2001 19:53:52 +0200 Dear all, When I perform a simulation analysis using subproblem option ( $SIMULATION (1879229) SUBPROBLEMS=100 ),NONMEM performs the first simulation (SUBPROBLEM=1) without any problem. But when NONMEM tries to execute the second simulation (SUBPROBLEM=2) the program stops and the following message is printed: ************************************************************************** PROBLEM NO.: 1 SUBPROBLEM NO.: 2 SIMULATION STEP PERFORMED SOURCE 1: SEED1: 1694998235 SEED2: 0 MONITORING OF SEARCH: 0SUBROUTINE GETETA NOT INITIALIZED **************************************************************************** Does anybody know how to resolve this problem? Thanks in advance. Josep Maria CendrĂ³s

Re: Simulation step

From: Joern Loetsch Date: October 22, 2001 technical
From: Joern.Loetsch@t-online.de (Joern Loetsch) Subject: Re: [NMusers] Simulation step Date: Mon, 22 Oct 2001 21:09:57 +0200 This is a known bug in NONMEM V. Go to http://www.cognigencorp.com/nonmem/nm/99jul291998.html anmd do what is advises Regards Joern _______________________________________________________ Jorn Lotsch, MD pharmazentrum frankfurt, Department of Clinical Pharmacology Johann Wolfgang Geothe-University Hospital Theodor-Stern-Kai 7 D-60590 Frankfurt Germany Phone: +49-69-6301-4589 Fax: +49-69-6301-7636