Senior Clinical Pharmacokineticist
Company Overview
Merrimack Pharmaceuticals is a privately held, biopharmaceutical company
aspiring to be the leading provider of personalized medicines. Our company is
advancing a suite of engineered therapeutics integrated with molecular
diagnostics designed to address significant medical needs in the treatment of
cancer and inflammation. Merrimack's integrated medicines (Rx & Dx) are
products of a paradigm changing R&D platform, Network Biology, which integrates
the technologies of engineering, biology, and computing to enable
mechanism-based, model driven discovery and development of both therapeutics
and diagnostics. We offer a highly collaborative, interdisciplinary environment
in which the treatment of cancer patients and improving the current paradigm of
drug development is paramount and central to all efforts.
Job Requirements:
Merrimack is running clinical trials across a number of oncology indications
both domestic and internationally. As part of the Clinical Investigations team,
the Senior Clinical Pharmacokineticist will support multiple Merrimack projects
in Phase 1 through Phase 3 development in oncology. This will include
supporting first in human studies, PK/PD studies and registration studies.
Job Responsibilities:
* Provide strategic guidance on study design
* Collaborate with clinical investigations, translational research and
clinical operations to develop and write protocols
* Analyze and interpret PK data for ongoing studies and generate PK reports
* Author clinical pharmacology sections for regulatory submissions
* Develop relevant PK models from pre-clinical data to simulate human PK
parameters
* Develop PK simulations from human data to inform dosing strategies
* Present PK data to project teams and other internal stakeholders
* Participate in meetings with regulatory authorities
Candidate Requirements:
* PhD in Pharmacology, Pharmaceutical Sciences or related discipline
* 10 years experience in all phases of clinical development, with a strong
preference for experience in Oncology
* Experience with biologics preferred
* Excellent interpersonal, communication, and organizational skills with the
ability to work independently and in a team environment
Apply online at:
https://merrimackpharma.tms.hrdepartment.com/jobs/167/Senior-Clinical-PharmacokineticistCambridge-MA