Final call: Second Workshop on Pharmacometrics, a tool for optimizing drug
development, Château de Longcol, La Fouillade (France), May 13-16, 2013:
http://pharmacometrica.webs.com
The workshop is intended for scientists in the pharmaceutical industry,
regulatory agencies, contract research organizations, and academia who are
expected to implement and apply model-based approach and to deploy
innovative pharmacometrics concepts and strategies for better supporting and
increasing the efficiency of drug development.
A Clinical Trial Simulator developed in R will be used to illustrate the use
of R in pharmacometrics, the population PK and PK/PD concepts, the
relevance of the inter and intra subject variability and the impact of
covariates on the clinical trial outcomes. As a working example, the
simulator will be used to generate data of a virtual clinical trial in
non-small cell lung cancer. The model will include a semi-mechanistic PK/PD
tumor growth component, the link between PK and adverse events and the link
between tumor growth and survival. The simulated virtual data will then be
used in a population analysis in NONMEM. The R scripts (including the trial
simulator) and the NONMEM control streams used will be distributed to the
participants.
For more information about the course, including the daily schedule, please
visit the workshop website: http://pharmacometrica.webs.com
Workshop venue: Château de Longcol (France): www.chateaudelongcol.com
Roberto Gomeni, PhD HDR
PharmacoMetrica
Longcol, 12270 La Fouillade (France)
E-mail: [email protected]
Mobile: +33(0) 760 45 1976
Fax: +33 (0) 983 23 3188
www.pharmacometrica.com