quest re delta clearance vs indep var

1 messages 1 people Latest: Jun 05, 1997

quest re delta clearance vs indep var

From: Christinalippert Date: June 05, 1997 technical
From christinalippert@hmri.com Thu Jun 5 13:52:34 1997 Subject: quest re delta clearance vs indep var I've gone through my notes from Short Course I attended in Nov 1993. In Lecture 17, Using NONMEM for Selecting Models, pg 6, discussion begins about scatter plotting the "delta CL" and "delta V" vs independent variables. Am I correct in assuming that I would calculate "delta CL" by subtracting TVCL from CL? With TVCL = THETA(1) and CL = TVCL*EXP(ETA(1)). Thanks for your help Chris Lippert Faltermeier, PhD US Clinical Pharmacokinetics mail station: F4-M3112 tele: x 7157, fax: x 6999 ****