Our Client in the Boston area is looking for a strong PhD level scientist to
deliver mechanistic and quantitative PK/PD/efficacy relationships to support
project teams from early discovery through early clinical development.
In addition, the individual will be involved in (PK) and (ADME) studies of to
support drug development from early discovery through preclinical and clinical
development. The individual will serve as DMPK project representative to
coordinate and lead all nonclinical DMPK activities on programs from research
phase through development. An individual with in-depth knowledge and expertise
in PK/PD modeling and simulation and ADME is essential.
Responsibilities:
Provide quantitative and mechanistic PK/PD/efficacy relationships to support
drug discovery and development teams
Design/execute preclinical studies to understand the (PK) and (ADME) of drug
candidates
Represent DMPK as the subject matter expert on project teams, develop and drive
DMPK and PK/PD strategy for Drug Discovery projects
Participate and manage CROs in the conduct of in vitro/in vivo ADME studies
Qualifications
PhD. with years of experience in the biopharmaceutical industry, with evidence
of modeling experience
Fluency with simulations and modeling, and in depth hands-on modeling
experience (e.g. using WinNonlin Phoenix, MATLAB/Simbiology, PK Sim, Simcyp, or
NONMEM to develop PK/PD models)
Solid knowledge of metabolism, ADM, PK/PD and bioanalytical principles is
required.
Experience with biologics desirable but not required.
Strong communication and presentation skills required
Excellent interpersonal skills
For more information please contact:
TJ Elder
Search Consultant
Pre-Clinical Development
O: 413.458.6124
C: 413.207.7676
https://www.linkedin.com/in/tjelder/
[email protected]<mailto:[email protected]>
[cid:[email http://www.stem-sourcing.com/
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