PRED in $TABLE from rich and sparse data

2 messages 2 people Latest: Oct 12, 2006

PRED in $TABLE from rich and sparse data

From: Xuemin Jiang Date: October 12, 2006 technical
From: "Jiang, Xuemin" xjiang1@medicine.bsd.uchicago.edu Subject: [NMusers] PRED in $TABLE from rich and sparse data Date: Thu, 12 Oct 2006 10:22:28 -0500 Dear NONMEM users, To my understanding, the PRED is the population mean value, so the PRED concentrations in the $TABLE should be same between subjects When dealing with reach data I got various PRED concentrations in the $TABLE between subjects. But when the data are sparse, I got almost same PRED concentrations in the $TABLE between subjects. Thanks Jim Jiang

Re: PRED in $TABLE from rich and sparse data

From: Serge Guzy Date: October 12, 2006 technical
From: Serge Guzy Subject: Re: [NMusers] PRED in $TABLE from rich and sparse data Date: Thu, 12 Oct 2006 I am not an expert in the $TABLE command but one reason could be that each individual got a different Dosage (Different dose or one got single dose and the other multiple dose) or route of administration. The population mean parameters are the same but the Pred at the same time will be different. Serge Guzy _______________________________________________________