----The Department of Clinical Pharmacy and Biochemistry of the Institute of Pharmacy at the Freie Universitaet Berlin is currently lookingfora: Postdoctoral Research Fellow(m/f/d)---
We are an interdisciplinary, international, research-oriented group applying high scientific standards and innovative methodologies with the ultimate aim to foster the rational use of medicines while empowering young scientists to perform clinically relevant research ( http://www.clinical-pharmacy.eu/ < http://www.clinical-pharmacy.eu/ >). Our group is grounded on two research pillars: (1) Bioanalysis, microdialysis, cell culture, and (2) Pharmacometric (data) analysis. As key feature, the two pillars are bridged, as our pharmacometric projects are based on in vivo or in vitro data obtained by the experimental research pillar, while innovative dynamic in vitro systems utilise modelling and simulation approaches. In addition, many of our projects are realised as parts of clinical studies. Typically, our research is embedded in consortia at a national and international level (EU, global).
We are looking for a full-time postdoctoral fellow in the field of optimising drug therapy and drug development by applyinginnovative translationalmodelling and simulation techniquesto join our research group for a period of at least 2year; extension to 5 years is possible. To be eligible for the position, a PhD and a strong record in the pharmacometric research area is needed. Additionally, experience in either or (i) evaluating pharmacokinetic, pharmacodynamic or systems pharmacology data and pharmacometric analysis with NONMEM, R or similar pharmacometric software,(ii) Bayesian analysis using STAN,or (iii) one of our experimental platforms (LC/MS-MS, microdialysis, bacterial infection models, in vitro metabolism)is required.
The position also offer supervision of PhD and Master/Diploma students. Applications in English should include a letter of motivation incl. a description of research interests and relevant qualifications for the position. In addition, a curriculum vitae including a list of publications and names/email addresses of 2-3 referees should be provided.
Please submit your application to: [email protected]
----Job profile----
•Performance and publication of research projects in pharmacometric and translational modelling
•Contribution to EU project “FAIR” of the Horizon 2020 initiative(11 European partnersfrom 6 different countries; Work package 5: Development of a translational modelling and simulation platform for flagellin PK/PD )
• Contribution to conception and realisation of new research ideas and collaborations•General services in research (co-supervision of junior members; IT/Cluster contact) and research organisation
----Qualification profile----
Requirements:
• Graduation in Pharmaceuticalor Life sciencesor related field
• Qualified PhD thesis in pharmacometrics, systems pharmacology or PBPK(PD) modelling, preferentially PK/PD modelling of therapeutic proteins
Assets:
• Profound knowledge in pharmacometrics software: e.g. NONMEM/PsN, Berkeley-Madonna
• Goodknowledge in the software programs R, PKSim,STAN, Monolix, Pirana
• In-depth experience in organisation and performance of research projects and in scientific publication in the area of pharmacometrics
• Experience with or interest for in vitrowork such as bacterial infection models, in vitro microdialysis or in vitro metabolism experiments
• High intrinsic motivation/high level of commitment
• Excellent team player
• Strong verbal/written communication skills
• Language skills: English excellent, no German required.
Dr. ir. Robin Michelet
Senior scientist
Freie Universitaet Berlin
Institute of Pharmacy
Dept. of Clinical Pharmacy & Biochemistry
Kelchstr. 31
12169 Berlin
Germany
Phone: + 49 30 838 50659
Fax: + 49 30 838 4 50656
Email:[email protected]
www.clinical-pharmacy.eu