Applications are invited for a position as pharmacodynamics modeling specialist
at the Precision Oncology Center of the Department of Oncology at CHUV,
Lausanne, Switzerland. The successful applicant will join a motivated and
unique multidisciplinary team of researchers working on data-centered precision
oncology, including machine learning and image analysis approaches. The work
will be in close collaboration with clinicians and scientists at CHUV and the
Merck Institute for Pharmacometrics, as part of a collaborative project called
"Real-World Tumor Dynamics". The objective is to create pharmacodynamics models
for the effect of immunotherapeutic agents, based on tumor measurements from
semi-automated analysis of medical images (PET/CT/MRI), and on treatment
schedules and other clinical covariates for retrospective CHUV patients. This
is one-year Post-doctoral position, but depending on the level of expertise of
the candidate, this could be combined as part of a PhD program.
Qualifications:
The candidate will have a recent PhD or at least a Master's degree in
quantitative discipline like engineering, pharmacology, computational biology,
applied mathematics, computer science, or a closely related field. The
applicant is expected to have qualifications, genuine interest, proficiency and
hands-on experience in the following topics:
* Pharmacokinetics/Pharmacodynamics (PK/PD) modeling methods
* Specialized Pharmacometrics software such as Monolix or NONMEM
* Mathematical software such as R or Matlab
Knowledge on medical information systems including ability to perform SQL
queries, as well as expertise in data science and programming in Python or
similar are assets.
Proficiency in spoken and written English is mandatory. French is an advantage.
Working Environment:
The precision Oncology Center collaborates with the following entities
* The Merck Institute for https://www.merckgroup.com/en,
located at the EPFL innovation park.
* Computational oncology & molecular modeling
https://www.unil.ch/dof/home/menuinst/our-research-groups/michielin.html
of the Department of Oncology at CHUV, Lausanne: part of the elite research
environment of the http://www.sccl.ch/index.php Swiss Cancer Center
http://www.sccl.ch/index.php.
* Service of Nuclear Medicine and Molecular Imaging
https://www.chuv.ch/fr/medecine-nucleaire/nuc-home/ at CHUV, Lausanne.
* Service of Radiodiagnostic and Interventional
https://www.chuv.ch/fr/rad/rad-home/ at CHUV, Lausanne. The service
is pushing forward infrastructure and expertise in machine learning at scale on
radiology data
* MedGIFT http://medgift.hevs.ch/wordpress/, Institute of
Information Systems, University of Applied Sciences Western Switzerland
(HES-SO), Sierre: collaborating with CHUV on image analysis pipelines and
radiomics.
Salary:
The offered salary is competitive, defined according to the Canton de Vaud
compensation grids.
More info and sending applications (by email):
Applications should include a letter of motivation, a curriculum vitae, and
names and addresses of two referees. If sufficient mutual interest develops
then referees will be contacted to assure suitability for the position.
Applications and enquiries should be addressed to:
Dr. Michel Cuendet
[email protected]<mailto:[email protected]>
Best Regards,
Nadia
Nadia Terranova, PhD
Associate Scientific Director Pharmacometry
Biopharma | R&D | Development Sciences | Translational Medicine
[cid:[email protected]]
Merck Institute for Pharmacometrics | EPFL Innovation Park - Building I |
CH-1015 Lausanne | Switzerland
Phone: +41.58.432.3706 | Mobile: +41.79.447.2621 | E-mail:
[email protected]<mailto:[email protected]> |
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