Position - Full Professor of Quantitative Systems Pharmacology at Leiden University

1 messages 1 people Latest: Oct 02, 2017
http://werkenbij.leidenuniv.nl/vacatures/wetenschappelijke-functies/17-379-full-professor.html The Faculty of Science, Leiden Academic Center for Drug Research is looking for a *Full Professor of Quantitative Systems Pharmacology (1.0 fte) Vacancy number: 17-379* Key responsibilities The research in the Systems Biomedicine & Pharmacology division builds on a strong history in pharmacokinetic-pharmacodynamic (PK-PD) computational modelling, and more recently, quantitative systems pharmacology (QSP). This research line aims to further on developing innovative QSP approaches. To that end, a position is available for a full professor in Systems Pharmacology, to maintain and further develop the research profile and reputation of this research at LACDR in that direction, together with the fellow principal investigators. Current research lines at the Cluster of Systems Pharmacology includes the following research themes: - Translational pharmacology; primary focus on experimental and model-based approaches the CNS therapeutic area; - Clinical pharmacology; model-based dose regimen optimization in special patient populations; - Quantitative Systems Pharmacology; QSP approaches in drug development (oncology, infectious diseases, cardiac safety); - Translational metabolomics; metabolomics in patients and patient-derived in-vitro models (organ-on-a-chip) to study disease mechanisms and pharmacology; - Systems biophysics; novel biophysics concepts to study immunology and metabolism. Selection Criteria - Experienced in quantitative modelling applied to (systems) pharmacology approaches; - Team player, dedicated supervisor and experienced in working with multi-disciplinary research teams; - Knowledge and ideally experience in state-of-the-art experimental approaches relevant to pharmacology and systems pharmacology; - Strong and established research lines and vision complementary to existing research lines. - A clear vision on how to further develop experimental capabilities in conjunction with computational QSP approaches, in the context of strengthening the collaborations within the cluster with the research lines on translational metabolomics and organ-on-a-chip approaches; - Proven ability or likely success to attract external research funding from funding agencies and industry; - Experienced in teaching; - Well established international network and research profile with a number of relevant high-quality publications; - Established career in academia or industry. Research at our Faculty and the LACDR The Faculty of Science is a world-class faculty where staff and students work together in a dynamic international environment. It is a faculty where personal and academic development are top priorities. Our people are driven by curiosity to expand fundamental knowledge and to look beyond the borders of their own discipline; their aim is to benefit science, and to make a contribution to addressing the major societal challenges of the future. The research carried out at the Faculty of Science is very diverse, ranging from mathematics, information science, astronomy, physics, chemistry and bio-pharmaceutical sciences to biology and environmental sciences. The research activities are organised in eight institutes. These institutes offer eight bachelor’s and twelve master’s programmes. The faculty has grown strongly in recent years and now has more than 1,300 staff and almost 4,000 students. We are located at the heart of Leiden’s Bio Science Park, one of Europe’s biggest science parks, where most companies have its focus on drug research. For more information, see https://www.universiteitleiden.nl/en/science and http://workingat.leiden.edu . The Leiden Academic Centre for Drug Research (LACDR) is a centre of excellence for multidisciplinary research on drug discovery and development. At LACDR, we develop innovative scientific concepts in fundamental and translational research underlying the discovery and optimization of drugs, and personalised medicines. We aim to optimise the route to novel drugs that are both efficacious and safe, and therefore our research focuses on drug and target discovery, bio-therapeutics and systems pharmacology. State-of-the-art expertise and infrastructures ensure that we are strategically positioned in (inter)national collaborations, thus further strengthening the development of novel concepts and their application in a clinical and industry environment. Our research is formed into three research clusters: Drug & Target Discovery, BioTherapeutics, and Systems Pharmacology. The Cluster of Systems Pharmacology focusses on personalised medicine and the development of novel systems-based approaches in translational and clinical pharmacology. LACDR has established close collaborations within the Faculty of Science (Leiden Institute of Chemistry, Institute of Biology Leiden), the Leiden University Medical Centre (LUMC) and the Centre for Human Drug Research (CHDR). Within the context of the so-called Medical Delta we have established alliances with LUMC and Erasmus MC in the area of translational epidemiology and the integration of metabolomics and genomics in large-scale longitudinal cohorts. More information about the LACDR can be found at https://www.universiteitleiden.nl/en/science/drug-research. Terms and conditions We offer a full-time temporary appointment for a period of 5 years with a view to a permanent contract depending on good performance and funding. Salary range from € 5,260.- to € 7,659.- gross per month (pay scale H2 in accordance with the Collective Labour Agreement for Dutch Universities). Leiden University offers an attractive benefits package with additional holiday (8%) and end-of-year (8.3 %) bonuses, training and career development and sabbatical leave. Our individual choices model gives you some freedom to assemble your own set of terms and conditions. Candidates from outside the Netherlands may be eligible for a substantial tax break. Diversity Leiden University is strongly committed to diversity within its community and especially welcomes applications from members of underrepresented groups. For more information: https://www.universiteitleiden.nl/en/science/about-faculty-of-science/diversity . Leiden University requires teaching staff to obtain the University Teaching Qualification (UTQ). If the successful applicant does not already possess this qualification or its equivalent, he/ she must be willing to obtain this qualification within two years. Information Enquiries can be made to prof. dr. Hubertus Irth, Scientific Director LACDR, [email protected], telephone: +31 71 527 4341. If you have any enquiries about the procedure, please contact prof. dr. Hubertus Irth, Scientific Director LACDR. Applications To apply for this vacancy, please send an email to prof. dr. H. Irth, [email protected]. Please ensure that you upload the following additional documents quoting the vacancy number: - Curriculum Vitae and list of publications; - Motivational letter; - Letters from at least two references. Only applications received *no later than 16 October 2017* can be considered. *Acquisition following this advertisement is not appreciated.*