Dear all,
The Disposition, Safety & Animal Research Department from Sanofi R&D is seeking
for a pharmacometrician within the Modeling & Simulation Unit of Paris
operational center. The candidate will have the following missions:
* Accountable for the development and implementation of a clinical
modeling and simulation plan based on agreed upon best practices (i.e.
model-based drug development).
* Responsible for designing and analyzing the pharmacokinetic and
pharmacodynamic components (population PK, PK/PD) of clinical trials in all
phases of development.
* Working and communicating effectively with people from diverse
scientific backgrounds in multi-disciplinary development teams providing
pharmacometric/modeling expertise in different therapeutic areas.
* Ensuring quality of the study protocols, reports, sections of reports
(e.g., INDs and NDAs) required for regulatory submissions to various health
authorities (e.g., the FDA and EMEA), summaries and publications.
* Implementing innovative quantitative methods to integrate data of
pharmacokinetics, biomarkers, and clinical outcome with data of patient
characteristics and knowledge of disease mechanisms and disease states to
facilitate quantitative decision making.
* Working in compliance with good clinical Practice (GCP) regulations
and guidance of regulatory authorities.
Qualifications
Requirements/Skills
* PhD in relevant scientific discipline and demonstrated expertise in
pharmacometrics and strong quantitative skills (e.g. experience in mechanistic
modelling/systems pharmacology, quantitative translational scaling, population
modelling).
* Understanding of DMPK and pharmacology/ safety aspects of drug
discovery and clinical development, and of basic statistics.
* At least 5 years of experience on modelling and simulation in drug
development in the pharmaceutical industry
* Excellent written and verbal communication skills, with successful
presentation capabilities.
* Excellent team work and strong communication in a multidisciplinary
environment
* Innovative and critical thinking. Customer focus.
* Languages: French and fluent English (oral and written)
To apply, please send your CV with references and a letter of motivation to
[email protected]<mailto:[email protected]> or
[email protected]<mailto:[email protected]> or
[email protected]<mailto:[email protected]>
or directly apply on the Sanofi website.
Christine Veyrat-Follet, PhD
Sanofi
Head of M&S group Paris