*An Introductory Workshop to Non-Linear Mixed Effects Modeling using
NONMEM® for Beginners*
We are pleased to announce a 2-day workshop introducing the basic concepts
and principles of non-linear mixed effects modeling using NONMEM and other
assisting software suites (e.g. R, PsN, Xpose & Pirana) for beginners with
limited experience in pharmacometrics. As part of the workshop, hands-on
sessions and case studies will be offered to familiarize the participants
with the principles and techniques associated with population modeling such
as data management, model coding, and interpretation of the results.
Location: The University Hospital of Cologne, 50924 Cologne, Germany.
Date: 11th and 12th of October, 2014
Instructors: The course will be organized and tutored by members of the
Clinical Pharmacology Unit in the University Hospital of Cologne, led by
Prof. Uwe Fuhr who has an extensive research profile and experience within
the field of clinical pharmacology. The unit has also been active in the
field of quantitative pharmacology and pharmacometrics over the last 10
years with significant contributions to the field.
Language of instruction: English
Workshop Outline:
· Introduction to (non-)linear regression modeling: basic
statistical principles, least squares and maximum likelihood fitting,
fixed and random effects, first order (conditional) estimation.
· Introduction to population pharmacokinetic modeling: exploratory
data analysis, introduction to NONMEM files (control stream and data file),
structural model development, random effects modeling.
· Model evaluation: introduction to supporting software tools (e.g.
R, Xpose, PsN & Pirana), goodness-of-fit plots, residual diagnostics,
bootstrapping analysis, simulation based diagnostics (e.g. visual
predictive checks).
· Covariate model building
· Introduction to modeling pharmacodynamics.
Workshop Fees
· 1000€ for participants from industry and commercial enterprises
· 500€ for academics and participants from non-profit organizations.
· 250€ for students in MSc or PhD programs.
Computers will not be provided and therefore we kindly ask you to bring
your own laptops with you and we will provide the necessary software on USB
sticks.
There are currently few places left, so we strongly recommend you to
register as soon as possible in case you are interested. For registration:
http://zks.uni-koeln.de/index.php?s=akademie&c=&id=135
https://owa.uk-koeln.de/OWA/redir.aspx?C=KaIFjMf1nkKKtlWzeHzuuBPSxEVzhtEIe1EGIC-36CD92cQ2IVgS2k8sIY56lhmc1kpoTlnNaW4.&URL=http%3a%2f%2fzks.uni-koeln.de%2findex.php%3fs%3dakademie%26c%3d%26id%3d135
The registration website is in German, and therefore if needed, we either
recommend using Google Chrome for example to help in translating the
different fields, or if in doubt, please contact [email protected]
https://owa.uk-koeln.de/OWA/redir.aspx?C=KaIFjMf1nkKKtlWzeHzuuBPSxEVzhtEIe1EGIC-36CD92cQ2IVgS2k8sIY56lhmc1kpoTlnNaW4.&URL=mailto%3auwe.fuhr%40uk-koeln.de
for further assistance.
Best Regards,
--
Ahmed Abbas Suleiman, MSc
PhD Candidate
Institute of Pharmacology - Clinical Pharmacology Unit
University Hospital of Cologne
Gleueler Str. 24, 50931 Cologne,
Germany
Phone: +49-221-478-3402
e-mail: [email protected]