NONMEM with the Intel fortran compiler with non-Intel (AMD) processors

1 messages 1 people Latest: Jan 05, 2010
The following may be of interest to anyone running NM with the Intel compiler on an AMD or other non-Intel processor. This apparently has come to light with Intel's recent $1.25 billion antitrust settlement to AMD . The FTC is currently looking into the Intel compiler issue and may require further action on Intel's part to correct its 'defective' compiler , which deliberately cripples performance on non-Intel chips. The effect is fairly large - improvements of about 50% in performance are observed with the AMD processors when the compiler is tricked into thinking it is compiling for an Intel processor. See http://www.agner.org/optimize/blog/read.php?i=49 for a more complete version - here is an excerpt: "Many software programmers consider Intel's compiler the best optimizing compiler on the market, and it is often the preferred compiler for the most critical applications. Likewise, Intel is supplying a lot of highly optimized function libraries for many different technical and scientific applications. In many cases, there are no good alternatives to Intel's function libraries. Unfortunately, software compiled with the Intel compiler or the Intel function libraries has inferior performance on AMD and VIA processors. The reason is that the compiler or library can make multiple versions of a piece of code, each optimized for a certain processor and instruction set, for example SSE2, SSE3, etc. The system includes a function that detects which type of CPU it is running on and chooses the optimal code path for that CPU. This is called a CPU dispatcher. However, the Intel CPU dispatcher does not only check which instruction set is supported by the CPU, it also checks the vendor ID string. If the vendor string says "GenuineIntel" then it uses the optimal code path. If the CPU is not from Intel then, in most cases, it will run the slowest possible version of the code, even if the CPU is fully compatible with a better version." Robert H. Leary, PhD Fellow Pharsight - A Certara(tm) Company 5625 Dillard Dr., Suite 205 Cary, NC 27511 Phone/Voice Mail: (919) 852-4625, Fax: (919) 859-6871 Email: [email protected] > This email message (including any attachments) is for the sole use of the > intended recipient and may contain confidential and proprietary information. > Any disclosure or distribution to third parties that is not specifically > authorized by the sender is prohibited. If you are not the intended > recipient, please contact the sender by reply email and destroy all copies of > the original message. >