NONMEM 7.1.2 run time in Windows 7

4 messages 3 people Latest: Mar 12, 2011

NONMEM 7.1.2 run time in Windows 7

From: Santosh Date: March 10, 2011 technical
Dear experts... We noticed that a NONMEM job (using NONMEM 7.1.2) runs much slower in Windows 7 loaded on a new HP workstation (z600 with >32GB RAM, Intel, 12 core CPU) when compared to running in Redhat Linux RHEL 5 on a 2 year old HP workstation (32 GB RAM, Intel 8 core CPU). It takes longer time to reach complete the first iteration with NONMEM on Windows 7. Can anyone please suggest possible reasons for runs being slow in Windows? Thanks, Santosh

RE: NONMEM 7.1.2 run time in Windows 7

From: Bill Denney Date: March 10, 2011 technical
Hi Santosh, One thing you didn't mention was the compiler. If you have an Intel compiler, things will typically run much faster. Thanks, Bill
Quoted reply history
From: [email protected] [mailto:[email protected]] On Behalf Of Santosh Sent: Thursday, March 10, 2011 10:01 AM To: [email protected] Subject: [NMusers] NONMEM 7.1.2 run time in Windows 7 Dear experts... We noticed that a NONMEM job (using NONMEM 7.1.2) runs much slower in Windows 7 loaded on a new HP workstation (z600 with >32GB RAM, Intel, 12 core CPU) when compared to running in Redhat Linux RHEL 5 on a 2 year old HP workstation (32 GB RAM, Intel 8 core CPU). It takes longer time to reach complete the first iteration with NONMEM on Windows 7. Can anyone please suggest possible reasons for runs being slow in Windows? Thanks, Santosh

RE: NONMEM 7.1.2 run time in Windows 7

From: Mark Sale Date: March 10, 2011 technical
I wasn't aware that there was a 12 core Intel CPU - maybe you have a dual processor 6 core? If you have a 12 core AMD CPU, you should be aware that this only has 6 floating point cores. In addition, if you use the Intel compiler with AMD CPUs, Intel cleverly disables all optimization, so the CPU seems slow (one of the many antitrust lawsuits AMD currently has against Intel). But, benchmarks and my experience suggest that AMD CPUs are substaintially slower than Intel, and, for us at least, 12 core AMD CPUs aren't really 12 core. Mark Sale MD President, Next Level Solutions, LLC www.NextLevelSolns.com 919-846-9185 A carbon-neutral company See our real time solar energy production at: http://enlighten.enphaseenergy.com/public/systems/aSDz2458
Quoted reply history
-------- Original Message -------- Subject: RE: [NMusers] NONMEM 7.1.2 run time in Windows 7 From: "Denney, William S." < [email protected] > ; Date: Thu, March 10, 2011 10:42 am To: "Santosh" < [email protected] >, < [email protected] > Hi Santosh, One thing you didn’t mention was the compiler. If you have an Intel compiler, things will typically run much faster. Thanks, Bill From: [email protected] [ mailto: [email protected] ] On Behalf Of Santosh Sent: Thursday, March 10, 2011 10:01 AM To: [email protected] Subject: [NMusers] NONMEM 7.1.2 run time in Windows 7 Dear experts... We noticed that a NONMEM job (using NONMEM 7.1.2) runs much slower in Windows 7 loaded on a new HP workstation (z600 with >32GB RAM, Intel, 12 core CPU) when compared to running in Redhat Linux RHEL 5 on a 2 year old HP workstation (32 GB RAM, Intel 8 core CPU). It takes longer time to reach complete the first iteration with NONMEM on Windows 7. Can anyone please suggest possible reasons for runs being slow in Windows? Thanks, Santosh

Re: NONMEM 7.1.2 run time in Windows 7

From: Santosh Date: March 12, 2011 technical
We noticed that gfortran installed on Windows 7 and Linux workstations are 32-bit and 64-bit, respectively. Are there ways to install 64-bit gfortran
Quoted reply history
on Windows 7? Regards, Santosh On Thu, Mar 10, 2011 at 9:42 AM, Santosh <[email protected]> wrote: > I forgot to mention.. > > Fortran compiler: gfortran 4.5.0 > The new workstation has dual Intel Xeon 6-core CPUs > > Thanks, > Santosh > > On Thu, Mar 10, 2011 at 7:01 AM, Santosh <[email protected]> wrote: > >> Dear experts... >> We noticed that a NONMEM job (using NONMEM 7.1.2) runs much slower in >> Windows 7 loaded on a new HP workstation (z600 with >24 GB RAM, Intel, 12 >> core CPU) when compared to running in Redhat Linux RHEL 5 on a 2 year old >> HP workstation (24 GB RAM, Intel dual quad core CPUs). It takes longer time >> to reach complete the first iteration with NONMEM on Windows 7. >> >> >> Can anyone please suggest possible reasons for runs being slow in Windows? >> >> >> Thanks, >> Santosh >> > >