Clinical Pharmacology = Disease Progression + Drug Action
by
Nick Holford, MBChB
University of Auckland, New Zealand
September 19, 2011
3:30 to 4:30 pm EDT
You are invited to attend Dr. Holford's webinar Clinical Pharmacology = Disease
Progression + Drug Action on September 19, 2011 at 3:30 pm EDT (GMT -5:00). Dr.
Holford’s talk will focus on modeling in clinical pharmacology. Like many
disciplines, clinical pharmacology can be viewed from several perspectives. In
the context of a clinical trial of a therapeutic agent, clinical pharmacology
provides a conceptual framework for relating drug treatment to responses and
differentiating possible mechanisms of action. Disease progression refers to
the evolution of a disease over time. It typically implies worsening of the
disease (but also may include spontaneous recovery). Disease progress on the
other hand is a description of the disease and its response to treatment. In
the context of simulation and modeling, it is useful to think of clinical
pharmacology as a model itself, i.e., the combination of disease progression
and drug action.
Dr. Holford's presentation is a part of the monthly world-wide webinar series
“Impact of Modeling & Simulation in Drug Development” hosted by Rosa & Co. LLC.
The purpose of the “Impact” series is to foster the use of M&S activities in
all phases of drug development by illustrating the advantages and enhancing the
applicability of M&S in product discovery, development, and marketing programs.
The series is intended for drug development project team members from discovery
to phase 4 clinical trials. This includes pharmacologists, ADME scientists,
PK/PD modelers, clinical pharmacologists, clinical development team members,
regulatory affairs specialists, and other interested professionals.
Register for this free webinar at www.rosaandco.com/webinar. After registering
you will receive a confirmation email containing information about joining the
webinar. More information about the webinar series, an archive of past
webinars, and a list of future webinar speakers may be found at
www.rosaandco.com/webinar.
Please allow 5-10 minutes for a Java applet to be installed on your computer
prior to joining our webinar series for the first time.
Toufigh Gordi, PhD
President, PK/PD and Clinical Pharmacology Services
Rosa & Co. LLC: www.rosaandco.com
E-mail: [email protected]
Tel.: 408-480-7314
Fax: 408-370-9810
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