Does anyone else have the 'feature' of negative iteration numbers in the
.ext file that nonmem writes?
Mostly the values are similar or identical to the preceding lines but not
always (see example below).
I am using nonmem 7.1.2 with gfortran 4.5.0, installed with nmqual 7.1.0
on Windows XP.
Thanks for any clues.
Andreas
TABLE NO. 1: First Order Conditional Estimation with Interact
ITERATION THETA1 THETA2 THETA3 THETA4
....OMEGA(10,10) OBJ
0 2.70000E+02 7.00000E+01 7.00000E+00 3.00000E+00
0.00000E+00 17903.085422267555
10 2.62990E+02 4.41321E+01 7.48823E+00 4.16453E+00
0.00000E+00 17596.998988682855
20 2.30575E+02 7.98655E+01 7.36614E+00 1.19184E+01
0.00000E+00 17573.820822902107
30 2.31353E+02 7.94068E+01 7.36395E+00 1.17636E+01
0.00000E+00 17573.797569595510
40 2.31992E+02 7.88078E+01 7.38680E+00 1.16398E+01
0.00000E+00 17573.754599870816
-1000000000 2.31992E+02 7.88078E+01 7.38680E+00 1.16398E+01
0.00000E+00 17573.754599870816
-1000000001 1.27442E+01 1.15823E+01 1.56697E-01 3.27570E+00
1.00000E+10 0.0000000000000000
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negative iteration numbers in .ext files
Does anyone else have the 'feature' of negative iteration numbers in the
.ext file that nonmem writes?
Mostly the values are similar or identical to the preceding lines but not
always (see example below).
I am using nonmem 7.1.2 with gfortran 4.5.0, installed with nmqual 7.1.0
on Windows XP.
Thanks for any clues.
Andreas
TABLE NO. 1: First Order Conditional Estimation with Interact
ITERATION THETA1 THETA2 THETA3 THETA4
....OMEGA(10,10) OBJ
0 2.70000E+02 7.00000E+01 7.00000E+00 3.00000E+00
0.00000E+00 17903.085422267555
10 2.62990E+02 4.41321E+01 7.48823E+00 4.16453E+00
0.00000E+00 17596.998988682855
20 2.30575E+02 7.98655E+01 7.36614E+00 1.19184E+01
0.00000E+00 17573.820822902107
30 2.31353E+02 7.94068E+01 7.36395E+00 1.17636E+01
0.00000E+00 17573.797569595510
40 2.31992E+02 7.88078E+01 7.38680E+00 1.16398E+01
0.00000E+00 17573.754599870816
-1000000000 2.31992E+02 7.88078E+01 7.38680E+00 1.16398E+01
0.00000E+00 17573.754599870816
-1000000001 1.27442E+01 1.15823E+01 1.56697E-01 3.27570E+00
1.00000E+10 0.0000000000000000
The information of this email and in any file transmitted with it is strictly
confidential and may be legally privileged.
It is intended solely for the addressee. If you are not the intended recipient,
any copying, distribution or any other use of this email is prohibited and may
be unlawful. In such case, you should please notify the sender immediately and
destroy this email.
The content of this email is not legally binding unless confirmed by letter.
Any views expressed in this message are those of the individual sender, except
where the message states otherwise and the sender is authorised to state them
to be the views of the sender's company. For further information about Actelion
please see our website at http://www.actelion.com
Andreas, you are not alone. We all have negative iterations. They are
just flags for the final parameter estimates (-1000000000) and their
standard errors (-1000000001) that can be used as parsing tags for other
programs.
I could not quickly find where this is documented.
Bill
Quoted reply history
-----Original Message-----
From: [email protected] [mailto:[email protected]]
On Behalf Of [email protected]
Sent: Friday, April 16, 2010 5:30 AM
To: [email protected]
Subject: [NMusers] negative iteration numbers in .ext files
Does anyone else have the 'feature' of negative iteration numbers in the
.ext file that nonmem writes?
Mostly the values are similar or identical to the preceding lines but
not
always (see example below).
I am using nonmem 7.1.2 with gfortran 4.5.0, installed with nmqual 7.1.0
on Windows XP.
Thanks for any clues.
Andreas
TABLE NO. 1: First Order Conditional Estimation with Interact
ITERATION THETA1 THETA2 THETA3 THETA4
....OMEGA(10,10) OBJ
0 2.70000E+02 7.00000E+01 7.00000E+00 3.00000E+00
0.00000E+00 17903.085422267555
10 2.62990E+02 4.41321E+01 7.48823E+00 4.16453E+00
0.00000E+00 17596.998988682855
20 2.30575E+02 7.98655E+01 7.36614E+00 1.19184E+01
0.00000E+00 17573.820822902107
30 2.31353E+02 7.94068E+01 7.36395E+00 1.17636E+01
0.00000E+00 17573.797569595510
40 2.31992E+02 7.88078E+01 7.38680E+00 1.16398E+01
0.00000E+00 17573.754599870816
-1000000000 2.31992E+02 7.88078E+01 7.38680E+00 1.16398E+01
0.00000E+00 17573.754599870816
-1000000001 1.27442E+01 1.15823E+01 1.56697E-01 3.27570E+00
1.00000E+10 0.0000000000000000
The information of this email and in any file transmitted with it is
strictly confidential and may be legally privileged.
It is intended solely for the addressee. If you are not the intended
recipient, any copying, distribution or any other use of this email is
prohibited and may be unlawful. In such case, you should please notify
the sender immediately and destroy this email.
The content of this email is not legally binding unless confirmed by
letter.
Any views expressed in this message are those of the individual sender,
except where the message states otherwise and the sender is authorised
to state them to be the views of the sender's company. For further
information about Actelion please see our website at
http://www.actelion.com