******************MEETING ANNOUNCEMENT*********************
The Second Annual Midwest Users Forum for Population Approaches in
Data Analysis will be held in Ann Arbor, Michigan on the 12th and 13th
of May, 1994. This meeting is intended to provide a forum for the
discussion of all aspects of population data analysis in an open and
informal atmosphere. The first meeting held in Indianapolis this past
April was highly successful and set the tone for this series as a
delightfully interactive discussion of the trials and tribulations of
population data analysis. Attendees are encouraged to step forward with
specific analyses or issues for podium presentation. It should be
recognized that these presentations serve as a spring board for extended
discussion. Generally, themes (e.g., mixed effect models, neural
networks, simulations, etc.) are of common interest and concern to all
those involved in the implementation of population approaches in data
analysis or the interpretation of results derived from such analyses.
The setting for this years forum is Ann Arbor, a short 5 hour drive from
the Indianapolis/Cincinnati region. If you choose to fly, Ann Arbor is
just 30 minutes from Detroit's International Airport. Depending on your
arrival time, the complimentary Sheraton shuttle service may be arranged
through Rhonda Reimann (Parke-Davis: 313-996-7044).
Much of the University of Michigan campus,
as well as a number of restaurants, bars, and night spots, will be just a
few minutes away. For those wishing to take advantage of stay-through-
Saturday super-saver airline fares, we are planning a golf outing at one
of the local courses (site, and therefore cost, to be determined by
participation level). Club rental will be available to those who wish to
golf but don't bring their own clubs. For less frustrating recreation, a
large regional shopping mall is within walking distance or, if there is
sufficient interest, we will arrange a trip (transportation provided) to the
popular Greenfield Village ($10) and Henry Ford Museum ($10) in
Dearborn.
The meeting will be held at the Ann Arbor Sheraton Inn (1-800-848-
2770), and a block of rooms has been reserved there at $57 per night.
A full breakfast is included in the room charge. Please identify yourself
as a MUFPADA attendee when reserving your room (must reserve by
April 18 to receive discounted rate).
A hospitality suite will be open from 5 to 9 Thursday evening. Join us
to renew old acquaintances and make new ones before heading out for
dinner. Meeting registration ($75) also includes lunch and two
refreshment breaks on Friday.
The registration form (request from sources below) also serves as a call for
papers. Those interested in sharing an experience should plan on
approximately 30 minutes for presentation and 15 to 30 minutes for
general discussion. Generally, success stories are presented, but if
individuals wish to bring a specific issue or problem into focus for
discussion, the forum will most likely respond with a multitude of
opinions. Please provide some information about your topic and one of
the organizers will contact you for specifics. Final program will be
determined by the number of presentations volunteered and will be
forwarded to all participants together with additional information and
maps in advance of the meeting.
For additional information please contact either:
Steve Olson or Alan Kugler
(313) 996-7623 (313) 996-7959
olsons@aa.wl.com kuglera@aa.wl.com
Follow-up by olsons@aa.wl.com (Steve Olson)
MIDWEST USERS FORUM FOR
POPULATION APPROACHES IN DATA ANALYSIS
The Second Annual Midwest Users Forum for Population Approaches in
Data Analysis will be held in Ann Arbor, Michigan on the 12th and 13th
of May, 1994. This meeting is intended to provide a forum for the
discussion of all aspects of population data analysis in an open and
informal atmosphere. The setting for this year's forum is Ann Arbor,
Michigan.
The forum will be held at the Ann Arbor Sheraton Inn (800-848-2770), and
a block of rooms has been reserved there at $57 per night (rate available
through April 22). A full breakfast is included in the room charge.
Please identify yourself as a MUFPADA attendee when reserving your room.
A hospitality suite will be open from 5 to 10 Thursday evening. Join us to
renew old acquaintances and make new ones before heading out for dinner.
Meeting registration ($75) also includes lunch and two refreshment breaks
on Friday. Registration forms and additional information may be obtained
by contacting Rhonda Reimann (313-996-7044) or Steve Olson
(olsons@aa.wl.com).
TENTATIVE MUFPADA PROGRAM
Thursday, May 12
12:30 Registration
1:00 Welcome and Introductions.
1:10 Absorption Models. Gordon Amidon, University of Michigan, Ann
Arbor, MI.
1:50 Application of Mixed Effect Modeling to Cross Study Assessment
of Phenytoin Bioequivalence. Jeff Koup, Parke-Davis, Ann Arbor,
MI.
2:30 Afternoon Break
3:00 TBA
3:40 Development of a Recursive, Pharmacodynamic Model for the
Analysis of Troglitazone, an Insulin Sensitizer. Steve Olson,
Parke-Davis, Ann Arbor, MI.
4:20 Close
5 to 10 Hospitality Suite and Mixer at the Sheraton
Friday, May 13
8:00 Registration and coffee
8:30 Welcome and Introductions.
8:40 Population Deconvolution: Absorption Time Course Estimation via
Nonlinear Mixed Effect Modeling. Bill Gillespie, FDA,
Silverspring, MD.
9:20 Testing for Population Equivalence of Effects of Two Treatments
Based on the Proportion of Similar Responses. Eunhee Huang,
Rhone-Poulenc Rorer, Collegeville, PA.
10:00 Morning Break
10:20 Gemcitabine Pharmacokinetics are Influenced by Gender, Body
Surface Area and Duration of Infusion. Sandy Allerheiligen, Eli
Lilly, Indianapolis, IN.
11:00 Population Pharmacokinetics of Teicoplanin and Its Application
in Drug Development. Dale Yu, Marion Merrill Dow, Kansas City,
MO.
11:40 Lunch in the Banquet Room
1:10 Pharmacokinetics of Phenytoin in Patients Receiving Fosphenytoin
for Prophylactic Control of Seizures Associated with
Neurosurgery.
Alan Kugler, Parke-Davis, Ann Arbor, MI.
1:50 Demonstration of Installation and Use of A Windows Interface for
NONMEM. Jeff Barrett, Summerset Pharmaceuticals, Tampa, FL.
2:30 Afternoon Break
2:50 Neural Networks in Population Pharmacokinetics. Ajaz Hussain,
University of Cincinnati, Cincinnati, OH.
3:30 An Overview of SAS's PROC MIXED and Other Mixed Effect
Modeling Routines. Lianng Yuh, Parke-Davis, Ann Arbor, MI.
4:10 Closing Business and Adjourn
Saturday, May 14
For those that plan to stay through Saturday a visit to Greenfield Village
and the Henry Ford Museum or golf at a local course has been arranged.