Actelion is looking for a (Senior) Modeling & Simulation Scientist at its
headquarters in the Basel (Switzerland) area.
Job Responsibilities
- Support compounds and projects in clinical development with
model-based data analysis
- Support decision making in clinical development by simulation of
scenarios and studies
- Contribute to decision making with quantitative assessments of
efficacy and safety measures of different doses, dosing regimens, and other
relevant variables
- Identify opportunities for model-based drug development
- Maintain effective communication with Life Cycle Teams, Clinical
Teams, and Clinical Trial Teams with the responsible Clinical Pharmacologist
- Ensure high quality contributions to drug development
- Management of quality and timelines
- Knowledge of relevant regulatory guidelines and requirements
- Sustain scientific competence by establishing familiarity with new
scientific developments
- Education of colleagues in Clinical Pharmacology and Clinical
Development about modeling and simulation
Candidate Requirements
- Relevant academic degree (pharmacology, statistics, pharmacometrics,
or similar)
- 3+ years of experience in applying modeling and simulation to drug
research and development
- Good knowledge of drug development and the transition phases
(preclinical to Phase I, Phase I to II)
- Experience with relevant software (Monolix, NONMEM, Berkeley Madonna,
R/S-PLUS, WinNonlin, other)
- Interest in collaboration across departments (DMPK, Clinical Science,
Biostatistics)
- Natural curiosity to learn, phrase questions, and discuss M&S
approaches with other scientists
- Good interpersonal and communication skills
- Fluency in English, written and spoken
- Knowledge of MS office products
About the Company
Actelion is a biopharmaceutical company founded in 1997, headquartered in
Allschwil/Basel, Switzerland. Today with about 2'500 people in 30 countries
we focus on discovery, development and marketing of innovative drugs for
highly unmet medical needs. Our successfully marketed compounds are
Tracleer(R) and Ventavis(R) and Veletri(R) for the treatment of pulmonary
arterial hypertension and Zavesca(R), the only approved oral treatment for
Gaucher disease and disease-modifying therapy for Niemann-Pick type C
disease. Actelion combines the innovation, entrepreneurial spirit and
flexibility of biotech with the financial, risk management, regulatory and
commercial discipline of a large pharmaceutical company. We have ambitious
plans to keep improving and growing - and are looking for people as
innovative as ourselves. What Actelion Offers
- A competitive salary and generous social benefits
- The possibility for development and advancement within our dynamic
organization
- The innovative and stimulating atmosphere of a multicultural
environment
The headquarters are located in Allschwil, Switzerland, a suburb of Basel,
on the borders of France and Germany.
Online Application Link
http://www.actelion.com/
http://www20.i-grasp.com/fe/tpl_actelion04.asp?newms=jj&id=54890&newlang=1
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Andreas Krause, PhD
Director, Lead Scientist Modeling and Simulation
Department of Clinical Pharmacology
Actelion Pharmaceuticals Ltd. * Gewerbestrasse 16 * CH-4123 Allschwil *
Switzerland
[email protected] * www.actelion.com
Address for visitors: Hegenheimermattweg 95
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