Mixture model with Pk parameter changing with time

1 messages 1 people Latest: May 24, 2004
From: Georg Hempel hempege@uni-muenster.de Subject: [NMusers] Mixture model with Pk parameter changing with time Date: Mon, May 24, 2004 11:01 am Dear all, In the NONMEM wish list dated 24 May 2002 posted by NONMEM Project Team (99may242002.html) I found: "Provide for mixture models at the observation level. NONMEM currently allows mixture models at the parameter level but not the observation level." Does this mean that NONMEM V does not work with a mixture model including Pk parameters changing with time after dose and is there a possibility to overcome this limitation? Thank you in advance Georg -- Hochschuldozent Dr. Georg Hempel Institut fr Pharmazeutische und Medizinische Chemie Hittorfstr. 58-62 48149 Muenster, Germany Phone: +49 251 83 55693 Fax.: +49 251 83 32144 E-mail: hempege@uni-muenster.de _______________________________________________________