Metrum Institute is offering the following on-site courses in Bar Harbor,
Maine, August 16-20, 2010. Please visit, http://training.metruminstitute.org,
to register.
August 16, 2010
MI200: Getting Started With Bayesian PK-PD Modeling & Simulation Using WinBUGS
(1 CR) provides an introduction to Bayesian modeling and the practical use of
WinBUGS for PK-PD applications. Participants may apply the 1 credit hour from
this course to the Metrum Institute Certificate Program in Pharmacometrics.
Metrum Institute encourages participants to also consider registering for
MI260: Bayesian Model-Based Meta-Analysis to Support Decision Making in Drug
Development offered in conjunction with this course.
Prerequisites: Experience with PK-PD modeling and some familiarity and hands-on
experience with nonlinear regression, mixed-effects modeling, and use of R (or
S-PLUS). Applicable MI courses include: MI220 or contact us.
Computer Hardware/Software: This course requires a Windows laptop computer with
an available USB 2.0 port. All required software used for hands-on examples
will be freeware/open-source software and simple instructions will be provided
for users to configure their computers before the course.
Location: College of the Atlantic, Bar Harbor, ME
August 17-18, 2010
MI255: Exposure-Response Modeling of Categorical, Count and Time-to-Event Data
Using Bayesian and Maximum Likelihood Methods (2 CR) is an intensive course
providing an introduction to modeling of categorical, count, and time-to-event
data, and the practical use of WinBUGS and NONMEM® for such applications. The
course provides some basic theory and illustrates some of the advantages of
using Bayesian methods for these types of data sets. Participants may apply the
2 credit hours from this course to the Metrum Institute Certificate Program in
Pharmacometrics.
Prerequisites: Experience with PK-PD modeling and some familiarity with
nonlinear regression, mixed-effects modeling, and R (or S-Plus) is required.
Prior experience with Bayesian modeling using Win- BUGS is desirable but not
required. The course includes a short introduction to Bayesian prin- ciples and
WinBUGS. Applicable MI courses include: MI200, MI210, MI212, MI220 and MI250,
or contact us.
Computer Hardware/Software: This course requires a Windows laptop computer with
an available USB 2.0 port. All required software used for hands-on examples
will be freeware/open-source software and simple instructions will be provided
for users to configure their computers before the course.
August 19-20, 2010
MI260: Bayesian Model-Based Meta-Analysis to Support Decision Making in Drug
Development (2 CR) provides an introduction to model-based meta-analysis of
summary data or a combination of summary and individual data from clinical
trials to support decision-making in clinical drug development. Upon completion
of the course, participants will be able to design a model-based meta-analysis
of clinical trial data to address strategic decisions in a clinical drug
development program and implement it using a Bayesian approach executed with
WinBUGS and R. Participants will also be able to construct a model for the
relationship between an efficacy- or safety-related clinical outcome and
independent variables such as dose, time and patient characteristics by
analysis of summary data from multiple studies, e.g., treatment means and
standard deviations, and construct such a model by analysis of a combination of
summary and individual data, as well as execute and interpret population
simulations to support decision-making in clinical drug development.
Participants may apply the 2 credit hours from this course to the Metrum
Institute Certificate Program in Pharmacometrics.
Prerequisites: Experience with PK-PD modeling and some familiarity and hands-on
experience with nonlinear regression, mixed effects modeling, Bayesian modeling
using WinBUGS, and use of R (or S-PLUS). MI200: Getting Started With Bayesian
PK-PD Modeling & Simulation Using WinBUGS, offered a few days prior to this
course, meets these requirements. Other applicable MI courses include: MI220
and MI250, or contact us.
Computer Hardware/Software: This course requires a Windows laptop computer with
an available USB 2.0 port. All required software used for hands-on examples
will be freeware/open-source software and simple instructions will be provided
for users to configure their computers before the course.
Location: College of the Atlantic, Bar Harbor, ME
William R Gillespie, VP Strategic Modeling & Simulation
Metrum Research Group LLC
2 Tunxis Road, Suite 112, Tariffville, CT 06081
Direct & FAX:919-371-2786, Main:860-735-7043
[email protected]
www.metrumrg.com