Log-transformation

3 messages 3 people Latest: May 10, 2002

Log-transformation

From: Rajeev Menon Date: May 10, 2002 technical
From: "Rajeev Menon" Subject: [NMusers] Log-transformation Date: Fri, 10 May 2002 13:45:22 -0400 Hello All, I was trying to do a log-transformation. My error statement was Y=LOG(F) + ERR(1) I get the following message when I try to run this runtime error M6202: MATH - log: SING error Image PC Routine nonmem.exe 0043F049 Unknown nonmem.exe 0043EE7B Unknown nonmem.exe 0043D878 Unknown Could anyone please tell me the best approach to overcome this. Thanks, Rajeev Menon, Ph.D. Pharmacokineticist PPD Development Clinical Pharmacology

RE: Log-transformation

From: William Bachman Date: May 10, 2002 technical
From: "Bachman, William" Subject: RE: [NMusers] Log-transformation Date: Fri, 10 May 2002 13:52:32 -0400 You are probably trying to take the log of zero. You need to protect the code for the points where F=0. Bill

Re: Log-transformation

From: Atul Bhattaram Venkatesh Date: May 10, 2002 technical
From: "Venkatesh Atul Bhattaram" Subject: Re: [NMusers] Log-transformation Date: Fri, 10 May 2002 14:46:23 -0400 Hello Rajeev You will need to include these in your error model. $ERROR CALLFL=0 IPRED = -3 IF(F.GT.0) IPRED = LOG(F) ; to avoid LOG(0) run-time error Y = IPRED + EPS(1) Venkatesh Atul Bhattaram Post-doctoral Fellow University of Florida Gainesville