Register for the CPT: Pharmacometrics & Systems Pharmacology Webinar
"Model Evaluation of Continuous Data Pharmacometric Models: Metrics and
Graphics"
Speaker: France Mentré, MD, PhD, University of Paris Diderot
Date and Time: Monday, December 4, 2017, 12:00 pm ET
Moderator: Piet van der Graaf, PhD, PharmD, Editor-in-Chief, PSP
Description: Join moderator Piet van der Graaf, PhD, PharmD, Editor-in-Chief of
CPT: Pharmacometrics & Systems
http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)2163-8306,
in welcoming France Mentré, MD, PhD, from University Paris Diderot as she
describes the first published
http://onlinelibrary.wiley.com/doi/10.1002/psp4.12161/full on model
evaluation in nonlinear mixed effect models (NLMEM), from the ISoP Model
Evaluation Group. This tutorial was developed by an international group of
experienced pharmacometricians from various backgrounds (academia, industry,
and regulatory agencies). It describes a core set of graphical tools for
evaluation of NLMEM for continuous data and provides guidance, especially to
beginner modelers, on how they are meant to be used. This presentation will
include a description of the different metrics, an illustration about their
graphical use on 'true and 'misspecified' models, and a discussion of their
pros and cons. The use of each graph is illustrated via two case examples,
which were chosen to illustrate the properties and behaviors of different
evaluation tools in different situations.
Registration Link:
http://www.ascpt.org/LinkClick.aspx?link=https%3a%2f%2fattendee.gotowebinar.com%2fregister%2f3793824575580960770&tabid=10295&portalid=8&mid=14719
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Lena Friberg, PhD
Professor in Pharmacometrics
Pharmacometrics research group
Dept of Pharmaceutical Biosciences
Uppsala University
Box 591
75124 Uppsala
Sweden
Phone: +46 18 471 4685
[email protected]<mailto:[email protected]>
http://www.farmbio.uu.se/research/researchgroups/pharmacometrics