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Dear all,
I wanted to ensure that you were aware of the significant opportunity available
through a role in the Pharmacometrics group based in La Jolla CA.
Pfizer Pharmacometricians have key roles to play in influencing the discovery
and development of drugs. It's fascinating, vital work and you could be part
of it. We have made the strategic decision to significantly enhance our
workforce in this discipline because of its critical importance to our
organization. Therefore we have several new positions for talented individuals
at a number of US sites.
Pharmacometricians (Individual Contributor) at La Jolla, CA
In this key role you will serve as the Pharmacometrics representative on
multidisciplinary discovery and/or development teams and provide Pharmacometric
expertise and leadership to a project. In the research units the position can
entail partnering with research based colleagues to select and validate
clinical targets in order to design efficient and informative proof of
mechanism and proof of concept studies. In the business units, the position
can entail partnering with development colleagues to integrate prior knowledge
in order to develop innovative clinical study designs for Phase II-IV clinical
trials by applying the principles of model based drug development.
Pharmacometricians work closely with Clinical Pharmacology Leads, Clinicians
and Statisticians to create clinical development plans that include assessments
of a drug's efficacy, safety, commercial viability and fulfilment of
registration requirements.
In order to achieve these aims, candidates are responsible for the use of
innovative analytical methods to integrate knowledge of pharmacokinetics,
pharmacodynamics, patient characteristics and disease states to optimize doses,
dosage regimens and study designs throughout clinical drug development.
Pharmacometricians routinely interact with internal governance bodies,
regulatory agencies and external opinions leaders. They are expected to
influence the external environment by advancing their discipline and through
external presentations and publications.
The ideal candidates will have a doctorate degree with demonstrated expertise
in Clinical Pharmacology and/or Pharmacometrics and strong quantitative skills
(e.g. experience in mechanistic modeling/systems pharmacology, quantitative
translational scaling, literature meta-analyses, population modeling, and
clinical trial simulations). Emphasis in the area of immuno-oncology is
preferred. We encourage applicants from different disciplines including
biostatistics, medicine, engineering, etc. Candidates with significant
experience are sought as well as recent graduates. In addition to professional
challenge, we offer a culture that supports and encourages ideas, and
recognizes individual contribution. Moreover, the salary and extensive benefits
are everything you'd expect from a world leading company
To apply please visit the careers pages on
http://www.pfizer.com and enter the following job opening
numbers:
For Pharmacometrics (Individual Contributor), job opening number: 1028623
Michael Amantea
Pharmacometrics, Global Clinical Pharmacology, Global Product Development,
Pfizer Inc, San Diego CA 92121