Building Mechanistic Physiological Models to Support Decisions in Drug
Discovery and Development:
A Proven Systems Pharmacology Approach
November 8-9, 2012 in Bridgewater, NJ
Instructor: Christine Friedrich PhD Chief Engineer Rosa and Co
In this workshop, participants will learn what mechanistic physiological
models are, how they are built, and how they can be applied. Participants
will also learn the Model Qualification Method (MQM), a systematic approach
for ensuring that a model is fit for the purpose for which it is intended.
Participants will work hands-on on a) planning a successful modeling project
for an example question, b) scoping the relevant biological components for
inclusion, c) translating biological relationships into mathematical
equations, d) analyzing data from literature for use in the model, e)
running simulations, f) performing sensitivity analysis, g) creating
multiple "virtual patients" to address uncertainty and variability, h)
interpreting model results, and i) qualitative and quantitative model
testing.
Please visit the ISoP website to learn more: http://www.go-isop.org/attend