Introduction course to Population PK and PK/PD modelling with NONMEM
During this three days course, participants will be introduced to the basic
principles of population approach nonlinear mixed effects modelling in
pharmacokinetic (PK) and pharmacodynamic (PD) evaluation of drugs and will have
opportunities for hands-on PK and PK/PD modelling and simulation examples
relevant to drug development. Topics include how to work with NONMEM and R,
data file preparation, model coding and visualization/interpretation of the
results.
Target audience
The course is intended for people who have a basic knowledge of PK, PD and data
analysis, and wish to extend their knowledge and skills on PK/PD in drug
development.
Course objectives
Aim of the course is to familiarize the participants with the basics of
population PK/PD modelling and to train the participants in working with NONMEM
to conduct population PK and PK/PD data analyses.
Details
Instructor Dr. Jasper Stevens
Duration 3 x 8 hours
Dates 6, 7 and 8 May 2020; 09:00-17:00
Location University Medical Center Groningen,
Groningen, The Netherlands
Language English
Maximum capacity 16 participants
Course overview
Session 1 Introduction to population PK modelling, NONMEM and R
Session 2 NONMEM work flow for population PK models; data
management, data exploration, model code and execution, output and
interpretation
Session 3 Population PK models continued: alternative
administration routes, solving differential equations using NONMEM and
simulations
Session 4 Population PK/PD models: introduction to PK/PD models and
implementation of direct effect models in NONMEM
Session 5 Population PK/PD models: effect compartment and indirect
response models
Course fee
The course fee is 1200 EUR, including course materials, coffee breaks, lunches
and one evening dinner (Wednesday evening). Computers are available, including
the required software packages.
A limited number of (PhD) students can register for a reduced fee (600 EUR),
for which a support letter of the supervisor has to be included upon
registration.
Cancellation received before April 10th, 2020 is subject to full refund,
cancellation received after this date is subject to 50% refund.
Registration
To register for the course, please send an email to
[email protected]<mailto:[email protected]> requesting a registration form.
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Jasper Stevens, PhD
University Medical Center Groningen
Clinical Pharmacy and Pharmacology
De Brug 50.1.D.15A; EB70
PO Box 30001
9700 RD Groningen
Tel: +31 50 361 7875
Fax: +31 50 361 4087
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