Hi,
I am not very familiar with NONMEM, but need to use NONMEM to do parametric
survival modeling. Can someone give me a simple example of how to do the
following with loglogistic distribution?
log(Y_i)=mu+ theta_1*X_{1i}+theta_2*X_{2i} +sigma*Z_i
where Y_i is the survival time for ith subject
mu is the intercept term
X_{1i} is the age for ith subject
X_{2i} is sex for the ith subject
sigma is the standard deviation for the error term Z_i
Z_i is the random error term with standard logistic distribution
If you have something similar or any other suggestions, that would be
greatly appreciated too!
Thanks a lot!
How to do parametric survival modeling
Dear Yi,
For the simple model you outline here, NONMEM might not be the most
efficient tool to use. A simple survival model like that can done in R
with one line of code.
Kind regards,
Filip
Quoted reply history
From: [email protected] [mailto:[email protected]]
On Behalf Of yi liu
Sent: Thursday, 3 November 2011 15:36
To: [email protected]
Subject: [NMusers] How to do parametric survival modeling
Hi,
I am not very familiar with NONMEM, but need to use NONMEM to do
parametric survival modeling. Can someone give me a simple example of
how to do the following with loglogistic distribution?
log(Y_i)=mu+ theta_1*X_{1i}+theta_2*X_{2i} +sigma*Z_i
where Y_i is the survival time for ith subject
mu is the intercept term
X_{1i} is the age for ith subject
X_{2i} is sex for the ith subject
sigma is the standard deviation for the error term Z_i
Z_i is the random error term with standard logistic distribution
If you have something similar or any other suggestions, that would be
greatly appreciated too!
Thanks a lot!