FDATA file missing

4 messages 3 people Latest: Nov 27, 2019

FDATA file missing

From: Mark Tepeck Date: November 26, 2019 technical
During my troubleshooting of a failed NONMEM run, I want to confirm the correct exclusion of some records (e.g., IGNORE CMT=2) for the input file. However, I could not find the FDATA file in the run directory. Is there any way to force NONMEM to generate a FDATA? I am also wondering about the possible causes of missing FDATA. Even the FDATA file is available, is it possible to include the column heads (e.g., ID, DV) on the top of the numbers? So, I can confirm which column is excluded or retained. In addition, I am not sure whether the dataset related warnings (e.g., DATA WARING 1, RECORD 100, DATA ITEM 11, THE DV IS NULL BUT MDV IS 0) is refereeing to the FDATA file or the raw input CSV file. In other words, the problematic record 100 represents the row 100 in the FDATA file or the CSV file? Thank you, Mark

Re: FDATA file missing

From: Sarah Cook Date: November 26, 2019 technical
Hi Mark, I'm guessing that you are probably running NONMEM via PsN. The default behavior of PsN is to suppress some output files, including the FDATA file. To request that the FDATA file be retained, you can include the option -extra_output=fdata on your PsN execute command line. I don't think there is any way to include the column headings (since they are ignored and not actually read into NONMEM), but having the FDATA file should help you troubleshoot your problem. As far as I know, the warnings relate to the location in the FDATA file, again, because the ignored rows are not actually being read in. Best of luck, Sarah Sarah F. Cook, PhD Adjunct Assistant Professor University at Buffalo Department of Pharmaceutical Sciences E-mail: [email protected] Phone: (570) 362-2981
Quoted reply history
________________________________ From: [email protected] <[email protected]> on behalf of Mark Tepeck <[email protected]> Sent: Tuesday, November 26, 2019 11:13 AM To: [email protected] Subject: [NMusers] FDATA file missing During my troubleshooting of a failed NONMEM run, I want to confirm the correct exclusion of some records (e.g., IGNORE CMT=2) for the input file. However, I could not find the FDATA file in the run directory. Is there any way to force NONMEM to generate a FDATA? I am also wondering about the possible causes of missing FDATA. Even the FDATA file is available, is it possible to include the column heads (e.g., ID, DV) on the top of the numbers? So, I can confirm which column is excluded or retained. In addition, I am not sure whether the dataset related warnings (e.g., DATA WARING 1, RECORD 100, DATA ITEM 11, THE DV IS NULL BUT MDV IS 0) is refereeing to the FDATA file or the raw input CSV file. In other words, the problematic record 100 represents the row 100 in the FDATA file or the CSV file? Thank you, Mark

Re: FDATA file missing

From: Mahmoud Tareq Abdelwahab Date: November 26, 2019 technical
Hello Mark, in addition to Sarah's suggestions, you could run NONMEM via psn using option clean=0 which will stop psn from cleaning the temp files generated by NONMEM. for the data issues, it refers to the actual data that's read into NONMEM i.e after excluding all ignore statements and dropped columns, a workaround is to filter out the dataset in the same way it's being filtered in the NMtran control stream or kill the run before it crashes and you should have the FDATA file in the NM folder. Mahmoud
Quoted reply history
On Tue, Nov 26, 2019 at 7:10 PM Cook, Sarah <[email protected]> wrote: > Hi Mark, > > > I'm guessing that you are probably running NONMEM via PsN. The default > behavior of PsN is to suppress some output files, including the FDATA file. > To request that the FDATA file be retained, you can include the option > -extra_output=fdata on your PsN execute command line. > > > I don't think there is any way to include the column headings (since they > are ignored and not actually read into NONMEM), but having the FDATA file > should help you troubleshoot your problem. As far as I know, the warnings > relate to the location in the FDATA file, again, because the ignored rows > are not actually being read in. > > > Best of luck, > > Sarah > > > > Sarah F. Cook, PhD > Adjunct Assistant Professor > University at Buffalo > Department of Pharmaceutical Sciences > E-mail: [email protected] > Phone: (570) 362-2981 > ------------------------------ > *From:* [email protected] <[email protected]> on > behalf of Mark Tepeck <[email protected]> > *Sent:* Tuesday, November 26, 2019 11:13 AM > *To:* [email protected] > *Subject:* [NMusers] FDATA file missing > > > During my troubleshooting of a failed NONMEM run, I want to confirm the > correct exclusion of some records (e.g., IGNORE CMT=2) for the input file. > However, I could not find the FDATA file in the run directory. Is there any > way to force NONMEM to generate a FDATA? I am also wondering about the > possible causes of missing FDATA. > > Even the FDATA file is available, is it possible to include the column > heads (e.g., ID, DV) on the top of the numbers? So, I can confirm which > column is excluded or retained. > > In addition, I am not sure whether the dataset related warnings (e.g., > DATA WARING 1, RECORD 100, DATA ITEM 11, THE DV IS NULL BUT MDV IS 0) is > refereeing to the FDATA file or the raw input CSV file. In other words, the > problematic record 100 represents the row 100 in the FDATA file or the CSV > file? > > Thank you, > > Mark > -- *Mahmoud Tareq AbdelwahabPhD StudentPharmacometrics Research GroupDivision of Clinical PharmacologyDepartment of MedicineUniversity of Cape TownK45 Old Main BuildingGroote Schuur HospitalObservatory, Cape Town 7925, South Africa.* *Tel: +27 21 650 4861Email: [email protected] <[email protected]>*

Re: FDATA file missing

From: Mark Tepeck Date: November 27, 2019 technical
Hi Mahmoud and Sarah, Thank you so much for your input. Both solutions do the job when I use Psn. -extra_output=fdata adds fdata to the root folder, while clean=0 keeps fdata in the Psn folder. I hope that Robert J. Bauer could consider the column heading feature for future NONMEM versions. I believe it would enable more efficient troubleshooting whenever needed. Best, Mark
Quoted reply history
On Tue, Nov 26, 2019 at 9:22 AM Mahmoud Tareq Abdelwahab < [email protected]> wrote: > Hello Mark, > > in addition to Sarah's suggestions, you could run NONMEM via psn using > option clean=0 which will stop psn from cleaning the temp files generated > by NONMEM. > > for the data issues, it refers to the actual data that's read into NONMEM > i.e after excluding all ignore statements and dropped columns, a workaround > is to filter out the dataset in the same way it's being filtered in the > NMtran control stream or kill the run before it crashes and you should have > the FDATA file in the NM folder. > > Mahmoud > > On Tue, Nov 26, 2019 at 7:10 PM Cook, Sarah <[email protected]> wrote: > >> Hi Mark, >> >> >> I'm guessing that you are probably running NONMEM via PsN. The default >> behavior of PsN is to suppress some output files, including the FDATA file. >> To request that the FDATA file be retained, you can include the option >> -extra_output=fdata on your PsN execute command line. >> >> >> I don't think there is any way to include the column headings (since they >> are ignored and not actually read into NONMEM), but having the FDATA file >> should help you troubleshoot your problem. As far as I know, the warnings >> relate to the location in the FDATA file, again, because the ignored rows >> are not actually being read in. >> >> >> Best of luck, >> >> Sarah >> >> >> >> Sarah F. Cook, PhD >> Adjunct Assistant Professor >> University at Buffalo >> Department of Pharmaceutical Sciences >> E-mail: [email protected] >> Phone: (570) 362-2981 >> ------------------------------ >> *From:* [email protected] <[email protected]> on >> behalf of Mark Tepeck <[email protected]> >> *Sent:* Tuesday, November 26, 2019 11:13 AM >> *To:* [email protected] >> *Subject:* [NMusers] FDATA file missing >> >> >> During my troubleshooting of a failed NONMEM run, I want to confirm the >> correct exclusion of some records (e.g., IGNORE CMT=2) for the input file. >> However, I could not find the FDATA file in the run directory. Is there any >> way to force NONMEM to generate a FDATA? I am also wondering about the >> possible causes of missing FDATA. >> >> Even the FDATA file is available, is it possible to include the column >> heads (e.g., ID, DV) on the top of the numbers? So, I can confirm which >> column is excluded or retained. >> >> In addition, I am not sure whether the dataset related warnings (e.g., >> DATA WARING 1, RECORD 100, DATA ITEM 11, THE DV IS NULL BUT MDV IS 0) is >> refereeing to the FDATA file or the raw input CSV file. In other words, the >> problematic record 100 represents the row 100 in the FDATA file or the CSV >> file? >> >> Thank you, >> >> Mark >> > > > -- > > > > > > > > > > > *Mahmoud Tareq AbdelwahabPhD StudentPharmacometrics Research GroupDivision > of Clinical PharmacologyDepartment of MedicineUniversity of Cape TownK45 > Old Main BuildingGroote Schuur HospitalObservatory, Cape Town 7925, South > Africa.* > > > *Tel: +27 21 650 4861Email: [email protected] <[email protected]>* > >