ETAs constructed from observed data

1 messages 1 people Latest: May 07, 2001

ETAs constructed from observed data

From: Joern Loetsch Date: May 07, 2001 technical
From: "Joern Loetsch" <j.loetsch@em.uni-frankfurt.de> Subject: ETAs constructed from observed data Date: Mon, 7 May 2001 11:53:58 +0200 Dear NONMEM users, I've got a model like Y=3DA+B*x I estimated A with nonmem as A=3DTHETA(1)*EXP(ETA(1)) but I know the individuila B from another experiment. How can I constract a 'pseudo-ETA' for my B. I'm uncertain whether I have to go with the variance or with the standard deviation of the observations of B. Thnax in advance Jorn Lotsch _______________________________________________________ Joern Loetsch, MD, PhD pharmazentrum frankfurt Department of Clinical Pharmacology J.W.Goethe-University Frankfurt/Main Theodor-Stern-Kai 7 D-60590 Frankfurt/Main, Germany Phone: +49-69-6301-4589 Fax: +49-69-6301-7636