Error in 'finedata' utility program

Hi Nmusers, I've tried to use the utility program 'finedata' to create a new data set with additional, non-observation, time points to be used for prediction purposes. It seemed to work fine at first, but then I realised that the values for DV and MDV at the inserted data records differed from the default. Instead of DV=. and MDV=1, the values were imputed using first observation carried backward. I struggled to figure out what was going wrong, and when I added MDV=1 to $FINEDATA I got the error message: 'DATA ITEM MDV COULD NOT BE FOUND'. In my original data set and model file TIME was data item number 10, DV was data item 19, EVID data item 20, and MDV data item 21. After reordering the columns so that the TIME, DV, EVID, and MDV data items all were among the first 6 data items in the data set/$INPUT, everything works fine and the outputted data set looks as expected. Is it possible to update this for future NONMEM versions, or at least include a note about it in the help files to avoid confusion? Apart from this, I can really recommend 'finedata'. It's a great utility program =) Thanks a lot, sa sa Johansson, PhD Clinical Pharmacometrician ----------------------------------------------------------------- AstraZeneca Research & Development | Quantitative Clinical Pharmacology Pepparedsleden 1, SE-431 83 Mlndal T: +46 (0)31 776 23 84 M: +46 (0)722 33 88 96 asa.johansson_at_astrazeneca.com Please consider the environment before printing this e-mail ________________________________ Confidentiality Notice: This message is private and may contain confidential and proprietary information. If you have received this message in error, please notify us and remove it from your system and note that you must not copy, distribute or take any action in reliance on it. Any unauthorized use or disclosure of the contents of this message is not permitted and may be unlawful.

Hi Nmusers, I've tried to use the utility program 'finedata' to create a new data set with additional, non-observation, time points to be used for prediction purposes. It seemed to work fine at first, but then I realised that the values for DV and MDV at the inserted data records differed from the default. Instead of DV=. and MDV=1, the values were imputed using first observation carried backward. I struggled to figure out what was going wrong, and when I added MDV=1 to $FINEDATA I got the error message: 'DATA ITEM MDV COULD NOT BE FOUND'. In my original data set and model file TIME was data item number 10, DV was data item 19, EVID data item 20, and MDV data item 21. After reordering the columns so that the TIME, DV, EVID, and MDV data items all were among the first 6 data items in the data set/$INPUT, everything works fine and the outputted data set looks as expected. Is it possible to update this for future NONMEM versions, or at least include a note about it in the help files to avoid confusion? Apart from this, I can really recommend 'finedata'. It's a great utility program =) Thanks a lot, Åsa Åsa Johansson, PhD Clinical Pharmacometrician ----------------------------------------------------------------- AstraZeneca Research & Development | Quantitative Clinical Pharmacology Pepparedsleden 1, SE-431 83 Mölndal T: +46 (0)31 776 23 84 M: +46 (0)722 33 88 96 [email protected] Please consider the environment before printing this e-mail ________________________________ Confidentiality Notice: This message is private and may contain confidential and proprietary information. If you have received this message in error, please notify us and remove it from your system and note that you must not copy, distribute or take any action in reliance on it. Any unauthorized use or disclosure of the contents of this message is not permitted and may be unlawful.