PhD/early stage research studentship available in a Marie Curie EU-funded joint project by University of Warwick, AstraZeneca, Fraunhofer-Chalmers Research Centre for Industrial Mathematics, and Swedish University of Agricultural Sciences on Modelling Dose Response Time Outcome Relationships.
Application deadline: 22nd February 2013
Start date: 1st June 2013
Duration: Three years
The project addresses the development and improvement of methodologies for analyzing dose-response-time data when systemic (plasma) exposure is sparse or lacking. Extending and applying tools and techniques from systems and control theory and in particular nonlinear estimation such as Kalman filtering will be central to developing methodology for this situation. Dose-response-time data analysis (DRT) enables us to more efficiently (quantitatively) analyze and draw conclusions about the underlying rate processes where traditional single-point assessment or area under the response-time curve approach generally fail. Hopefully, this also allows a more robust design tool for future pharmacodynamic experiments in both animals and man. The candidate student should have a strong background (MSc or equivalent) in biological engineering/numerical techniques/computing science/chemical engineering, and life science courses. A track record in pharmacokinetics/dynamics would also be beneficial.
(Closing date: Feb 22, 2013)
For further details and online application see < http://www.jobs.ac.uk/job/AFU050/marie-curie-fp7-people-eid-phd-early-stage-research-studentship/ >.
Questions can be directed to Mats Jirstrand ( [email protected] ) or Johan Gabrielsson ( [email protected] ).
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Mats Jirstrand, PhD, Assoc Prof
Head of Department Systems and Data Analysis
Fraunhofer-Chalmers Research Centre
for Industrial Mathematics Phone: +46-(0)31-7724250
Chalmers Science Park Fax: +46-(0)31-7724260
SE-412 88 Göteborg Email: [email protected]
SWEDEN Web: www.fcc.chalmers.se/sys