Difficulty with ADVAN6

2 messages 2 people Latest: Feb 16, 2005

Difficulty with ADVAN6

From: Partha Nandy Date: February 16, 2005 technical
From: "Partha Nandy" partha.nandy@bms.com Subject: [NMusers] Difficulty with ADVAN6 Date: Wed, February 16, 2005 12:39 pm Hi All, I am running ADVAN6 and was trying to increase the IMAX default from 100000 to 200000 using the following code:- "FIRST "COMMON/PRCOMG/IDUM1.IDUM2,IMAX,IDUM4,IDUM5 "INTEGER IDUM1,IDUM2,IMAX,IDUM4,IDUM5 "IMAX=200000 but I keep getting the same error; do not see the change being reflected... "NUMERICAL DIFFICULTIES WITH INTEGRATION ROUTINE. MAXIMUM NO. OF EVALUATIONS OF DIFFERENTIAL EQUATIONS, 100000, EXCEEDED" I appreciate your help very much. Kind Regards, Partha Partha Nandy BMS-Clinical Discovery Lawrenceville, NJ

Re: Difficulty with ADVAN6

From: Phil Lowe Date: February 16, 2005 technical
From: phil.lowe@pharma.novartis.com Subject: Re: [NMusers] Difficulty with ADVAN6 Date: Wed, February 16, 2005 1:38 pm Dear Partha, I had this problem some years ago and asked nmusers. The answer was simple - there is a space missing between the " and the command. Thus $PK " FIRST " COMMON /PRCOMG/ IDUM1,IDUM2,IMAX,IDUM4,IDUM5 " INTEGER IDUM1,IDUM2,IMAX,IDUM4,IDUM5 " IMAX=1000000 Should work. However, if the integrator has to work that hard and divide down into such small steps, there might be something wrong with the model. It will certainly take longer to run. Best regards, Phil. _______________________________________________________