Applications of Minimal PBPK Models to Small and Large Molecules
by
Dr. Yanguang Cao
Research Assistant Professor
Department of Pharmaceutical Sciences
State University of New York at Buffalo
Buffalo, NY
December 11, 2013
1:00 - 2:00 pm EST
Dr. Cao's webinar "Applications of Minimal PBPK Models to Small and Large
Molecules" will take place on Wednesday, December 11, 2013 at 1:00 pm - 2:00 pm
EST.
>From Dr. Cao, "Minimal PBPK model is an intermediate modeling approach between
>full-PBPK model and mammillary model. This modelling approach is conceptually
>developed by substantially lumping full PBPK model. Most importantly, minimal
>PBPK model provides a sensible modeling approach when fitting ONLY plasma (or
>blood) data but yielding physiologically-relevant PK parameters. These
>parameters may provide more practical value than that generated in mammillary
>models. This talk will be about applying this modeling approach to both small
>molecules and monoclonal antibodies PK analysis."
Dr. Cao's presentation is a part of the monthly world-wide webinar series
"Impact of Modeling & Simulation in Drug Development" hosted by Rosa & Co. LLC.
The purpose of the "Impact" series is to foster the use of M&S activities in
all phases of drug development by illustrating the advantages and enhancing the
applicability of M&S in product discovery, development, and marketing programs.
The series is intended for drug development project team members from discovery
to phase IV clinical trials. This includes pharmacologists, ADME scientists,
PK/PD modelers, clinical pharmacologists, clinical development team members,
regulatory affairs specialists, and other interested professionals.
Register for this free webinar at www.rosaandco.com/webinar. After
registering you will receive a confirmation email containing information about
joining the webinar. More information about the webinar series, an archive of
past webinars, and a list of future webinar speakers may be found at
http://www.rosaandco.com/webinar.
Toufigh Gordi, PhD
President, PK/PD and Clinical Pharmacology Services
Direct: 408-480-7314
Corp: 408-370-9800
Fax: 408-370-9810
[email protected]