Friends:
I am new to NONMEM. I am trying to create a data file for a drug that is dosed
as follows.
Stress or loading dose Q 6hrs x 48 hours. Then maintenance dose is started as a
Q 6h regimen 12 hours after the last loading dose. The plasma conc is measured
after 3-4 maintenance doses are administered.
I am trying to develop an excel data sheet as follows.
C ID AMT Time ADDL II DV Ht WT Age
Here for amount (AMT) how do I include the stress or LD information? Do I
create a separate data line for these doses?
Any help is appreciated.
Varsha Mehta
Varsha Mehta, Pharm.D., FCCP
Clinical Associate Professor
Pharmacy, Pediatrics and Communicable Diseases
Clinical Pharmacist, Pediatric/Neonatal Critical Care
University of Michigan
(O) 734-936-8985
(F) 734-936-6946
[EMAIL PROTECTED]
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