Dear All
We are running our next ‘Intensive 5-day Workshop on Model-Informed Drug
Development’ in Krakow, Poland, 13-17 May 2019.
Delegates will learn a range of topics including:
- Metabolic drug clearance (CL)
- Metabolic drug-drug interactions (DDIs)
- Gut first-pass metabolism
- Oral drug absorption incorporating food effects and the impact of
dosage form
- Effect of transporters and enterohepatic recirculation on kinetics and
DDIs
- Drug distribution to different organs
- Population variability in drug concentration-time profiles
- Variation in kinetics in specific populations (pediatrics, ethnic
groups, various disease populations)
- Modeling of therapeutic proteins
- Pharmacodynamic effects of different compounds
- Time-course of drug in plasma that fits observed clinical data
(achieved by combining fitting techniques with IVIVE, PBPK and
drug-specific in vitro data)
*For more information please visit: *
* https://www.certara.com/wp-content/uploads/Resources/Workshops/FL_SimcypWorkshop-KrakowA2019.pdf*
https://www.certara.com/wp-content/uploads/Resources/Workshops/FL_SimcypWorkshop-KrakowA2019.pdf
Regards
Masoud