Company: PAREXEL
Job Title: Principle Pharmacokinetic Scientist
Department: Scientific Services - Clinical PK/PD and Pharmacometrics
Location: UK, Uxbridge and US, East Coast
Essential Function
Primary role of the PK Scientist
* Provision of support to clinical study design and the analysis and
interpretation of PK and PD data for Early Phase studies.
* Provide consultative support for PK data interpretation to other SBUs and
clients
Key Accountabilities:
* To analyze clinical PK/PD data as a member of several multidisciplinary
development program teams.
* To work with our clinical team to design PK components in various study
designs such as first-in-human, bioequivalence and drug-drug interaction
studies. The selected individual will be responsible for authoring or
contributing to clinical PK/PD sections of relevant documents.
* Serve as a primary source of scientific support for the design, analysis,
reporting, and presentation of sophisticated pharmacokinetic and
pharmacodynamic modelling and simulation initiatives, including population
pharmacokinetic/pharmacodynamic analyses for both phase I and late phase
clinical trials
* To provide training and scientific support and advice to all Early Phase
staff
* Review of scientific documentation including Clinical Study Protocols,
SOPs, Statistical Analysis Plans and Clinical Study Reports
* Quality control of pharmacokinetic output from WinNonlin analysis
* Review of derived PK data generated by PK Analyst
* To attend client meetings and represent PK/PD aspects as needed
Skills:
* Strong Knowledge of drug pharmacokinetics
* Experience in Pharsight Software (WinNonlin/Phoenix)
* Understanding of pharmacokinetic, and PK/PD modelling strategies
* Experience in other software such as NONMEM, S-PLUS (population
pharmacokinetics)
* Experience in early clinical drug development of both NCEs and biologicals
Education:
* Science degree or preferably higher scientific qualification
Language Skills
* Good standard of written and spoken English
Desired Work Experience
* 5+ years in Clinical Pharmacology, 5+ years pharmacokinetics experience
For more information visit
http://sh.webhire.com/servlet/av/jd?ai=206&ji=2641743&sn=I
Please contact Jon Gibbs for more details;
Jon Gibbs
PAREXEL International
The Quays
101-105 Oxford Road
Uxbridge
Middlesex
UB8 1LZ
Email: [email protected]<mailto:[email protected]>
Direct: +44(0)1895 614968