Sr. Director Quantitative Pharmacology / Pharmacometrics-Cambridge Massachusetts

Our client is growing rapidly! This newly created position will report to the Head of Quantitative Pharmacology Position Summary strategic and scientific job, responsible for quality of modeling work being performed. This person will apply state of the art modeling and simulation (M&S) approaches to influence designs and internal/external decision making across the portfolio. We expect this person to develop and apply quantitative frameworks that enable model-informed drug discovery and development. In addition, this position will ensure quantitative rigor and quality results through direct scientific mentorship JOB DUTIES - Accountable for developing a culture encouraging approaches influencing key partners, stakeholders and regulators of its value and application - Accountable for planning and executing state-of-the-art M&S techniques with direct value for projects cross the portfolio - Scientific and strategic input into pre-clinical, clinical, and post-approval development plans - Accountable for oversight, support and delivery of scientific and strategic modeling work related to specific projects - Support evaluation of drug candidates for in/out-licensing - Accountable for the identification and development of drug-disease models and other modeling approaches to support internal and external decision making in collaboration with partners (when relevant) - Accountable to provide peer review and mentoring of junior staff - Support and contribute to the development of the quantitative pharmacology in terms of providing training and knowledge sharing - Monitoring external and internal environment in terms of relevant new methodologies and applications - Increase profile externally in the area by speaking at external events and by publication in recognized external journals - Ensure modeling efforts are aligned with current regulatory expectation - Partner with the Preclinical Pharmacokinetic/Pharmacodynamics Team to enable translational PKPD efforts in the Discovery space REQUIREMENTS Education This position requires a PhD in Pharmaceutical Sciences (PKPD emphasis), Statistics, Engineering or other quantitative subject areas. 15 years validated experience in the application of QP in a drug discovery/development setting including experience in developing PhD modelers is required. This experience should include noteworthy expertise in M&S, including PK, PKPD and Statistics. Broad Translational and Clinical development expertise in drug development (early and late), with emphasis on Pharmacometrics is required. The candidate will have an international reputation gained from publishing in the field on Pharmacometrics as well as a track record of identifying, developing and executing portfolio-level M&S activities and disease domain knowledge. A confirmed knowledge of Regulatory, compliance, processes, standards and Pharmacometrics issues as well as Regulatory experience (written/oral) is desired. For more information please contact: TJ Elder President Clinical Pharmacology / Pharmacometrics O: 413.458.6124 C: 413.207.7676 https://www.linkedin.com/in/tjelder/ [email protected]<mailto:[email protected]> [cid:[email http://www.stem-sourcing.com/ Please Note: The information in this e-mail message is legally privileged and confidential information intended only for the use of the addressee(s) named above. If you, the reader of this message, are not the intended recipient, you are hereby notified that you should not further disseminate, distribute, or forward this e-mail message. If you have received this e-mail in error, please notify the sender as soon as possible. In addition, please delete the erroneously received message from any device/media where the message is stored.